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About This Item
Empirical Formula (Hill Notation):
C14H18N5O2 · HCl
CAS Number:
Molecular Weight:
324.79
UNSPSC Code:
41106305
PubChem Substance ID:
MDL number:
assay
≥98% (TLC)
form
solid
color
white
mp
193-194 °C
solubility
H2O: >20 mg/mL (Solutions should be freshly prepared.)
storage temp.
room temp
SMILES string
Cl.CCOC(=O)c1cnc2n(CC)ncc2c1N\N=C(\C)C
InChI
1S/C14H19N5O2.ClH/c1-5-19-13-10(8-16-19)12(18-17-9(3)4)11(7-15-13)14(20)21-6-2;/h7-8H,5-6H2,1-4H3,(H,15,18);1H
InChI key
GQJUGJHJUZSJLZ-UHFFFAOYSA-N
Gene Information
human ... GABRB3(2562), PRKAR1A(5573), PRKAR1AP(5574), PRKAR1B(5575), PRKAR2A(5576), PRKAR2B(5577)
Biochem/physiol Actions
Selective inhibitor of cAMP-specific phosphodiesterase.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk
WGK 3
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Anxioselective anxiolytics.
M Williams
Journal of medicinal chemistry, 26(5), 619-628 (1983-05-01)
[Pharmacologic value of cyclic nucleotide phosphodiesterase inhibitors].
G Nemoz et al.
Annales pharmaceutiques francaises, 42(2), 99-112 (1984-01-01)
P L Wood et al.
Progress in neuro-psychopharmacology & biological psychiatry, 8(4-6), 785-788 (1984-01-01)
The efficacy of coupling between the benzodiazepine receptor and chloride channel as well as the coupling to the GABA receptor is differentially affected by different benzodiazepine ligands. In general, the order of efficacy with regard to allosteric effects of benzodiazepine
Global Trade Item Number
| SKU | GTIN |
|---|---|
| E1896-1MG | 04061826744499 |
| E1896-5MG | 04061832897912 |
