E0518

C1 Esterase Inhibitor

aqueous solution, ≥95% (SDS-PAGE)

• Synonym(s): Complement C1 esterase inhibitor, Esterase inhibitor C-1 from human plasma
• CAS Number: 80295-38-1
• UNSPSC Code: 12352202
• NACRES: NA.77
• MDL number: MFCD00212908

Properties

• Product Name: C1 Esterase Inhibitor from human plasma, aqueous solution, ≥95% (SDS-PAGE)
• biological source: human plasma
• Quality Segment: 200
• assay: ≥95% (SDS-PAGE)
• form: aqueous solution
• mol wt: ~105 kDa
• UniProt accession no.: P05155
• shipped in: dry ice
• storage temp.: −20°C
• Gene Information: human ... SERPING1(710)

Description

Biochem/physiol Actions

Esterase inhibitor C1 is a multifunctional regulator of all major kinin-generating protein cascade systems. It has been a therapeutic tool in the treatment of hereditary angioedema and complement-mediated inflammatory tissue damage such as capillary leak syndrome, septic shock, multiple organ failure, and hyperacute graft rejection.

Physical form

Solution in 20 mM potassium phosphate, pH 7.0, containing 250 mM KCl

Disclaimer

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable