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biological source
plant (Croton tiglium L)
form
viscous liquid
density
0.94 g/mL at 25 °C (lit.)
functional group
ester
lipid type
oils
shipped in
ambient
storage temp.
room temp
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General description
Croton oil is a toxic viscous liquid extracted from seeds of Croton tiglium. It is pale yellow to brown in color and is transparent in nature. Croton oil has a strong irritant property and is used along with phenol in some chemical peels. It also has a tumor promoting ability.
Croton oil is extracted from Croton tiglium L. It consists of crotonoleic acid, crotonic acid, crotonyl alcohol, crotonyl alcohol bisester and crotonyl alcohol trisester. Croton oil acts as a stimulant in the skin and mucosal inflammation. It is associated with allergic contact dermatitis (ACD) and skin carcinoma. Croton oil functions as a skin peeling agent.
Application
Croton oil has been used to induce acute skin inflammation.
Croton oil has been used to induce inflammation in mouse ears.
Other Notes
Essential oil rich in glycerides of saturated fatty acids, and in phorbol esters.
Storage Class
10 - Combustible liquids
wgk_germany
WGK 3
flash_point_f
165.2 °F - closed cup
flash_point_c
74 °C - closed cup
ppe
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
Certificates of Analysis (COA)
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The inhibition of croton oil-promoted mouse skin tumorigenesis by steroid hormones
Belman S and Troll W
Cancer Research, 32(3), 450-454 (1972)
Croton oil peels
Bensimon RH
Aesthetic Surgery Journal / The American Society for Aesthetic Plastic Surgery, 28(1), 33-45 (2008)
Heparanase expression in B16 melanoma cells and peripheral blood neutrophils before and after extravasation detected by novel anti-mouse heparanase monoclonal antibodies
Komatsu N, et al.
Journal of Immunological Methods, 331(1-2), 82-93 (2008)
Phillip R Langsdon et al.
Facial plastic surgery : FPS, 28(1), 116-125 (2012-03-16)
Chemexfoliation is an excellent method to reduce facial rhytids. For 25 years, we have used the traditional formula as described by T. J. Baker but with a moist healing technique rather than a tape mask. We have found the peel
An examination of the phenol-croton oil peel: Part I. Dissecting the formula
Hetter GP
Plastic and Reconstructive Surgery, 105(1), 227-239 (2000)
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