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C4418

Sigma-Aldrich

L-Cysteinesulfinic acid monohydrate

Synonym(s):

3-Sulfinoalanine

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About This Item

Empirical Formula (Hill Notation):
C3H7NO4S · H2O
CAS Number:
207121-48-0
Molecular Weight:
171.17
MDL number:
MFCD00044889
UNSPSC Code:
12352209
PubChem Substance ID:
24278312
NACRES:
NA.32

form

powder

storage temp.

−20°C

SMILES string

NC(CS(O)=O)C(O)=O

InChI

1S/C3H7NO4S/c4-2(3(5)6)1-9(7)8/h2H,1,4H2,(H,5,6)(H,7,8)

InChI key

ADVPTQAUNPRNPO-UHFFFAOYSA-N

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Application

L-Cysteinesulfinic acid monohydrate has been used in the fluorescence measurement of cysteine oxidation.

Biochem/physiol Actions

Cysteinesulfinic acid (CSA), also called 3-sulfinoalanine is synthesized by the conversion of sulfur to sulfinic acid in cysteine by the enzyme cysteine dioxygenase (CDO). CSA is a putative excitatory amino acid (EAA) with neurotransmitter functionality. It also regulates cardiovascular functions.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Cardiovascular actions of L-cysteine and L-cysteine sulfinic acid in the nucleus tractus solitarius of the rat
Takemoto Y
Amino Acids, 46(7), 1707-1713 (2014)
Oxidation of hypotaurine and cysteine sulphinic acid by peroxynitrite
Fontana M, et al.
The Biochemical Journal, 389(1), 233-240 (2005)
Cysteine sulphinate (CSA) as an excitatory amino acid transmitter candidate in the mammalian central nervous system.
R Griffiths
Progress in neurobiology, 35(4), 313-323 (1990-01-01)
Cysteine dioxygenase: a robust system for regulation of cellular cysteine levels
Stipanuk MH, et al.
Amino Acids, 37(1), 55-55 (2009)
N-acetyl cysteine functions as a fast-acting antioxidant by triggering intracellular H2S and sulfane sulfur production
Ezericna D, et al.
Cell Chemical Biology, 25(4), 447-459 (2018)

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