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B4813

BGP-15

≥98% (HPLC)

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5 mg

Available to ship TODAYfromMILWAUKEE

$192.00
$163.20
25 mg

Available to ship TODAYfromMILWAUKEE

$771.00

About This Item

Empirical Formula (Hill Notation):
C14H22N4O2· 2HCl
CAS Number:
66611-37-8
Molecular Weight:
351.27
NACRES:
NA.77
PubChem Substance ID:
329773244
UNSPSC Code:
12352200
MDL number:
MFCD21603901
Assay:
≥98% (HPLC)
Form:
solid

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Quality Segment

100

assay

≥98% (HPLC)

form

solid

solubility

deionized water: 28 mg/mL

storage temp.

−20°C

SMILES string

Cl.Cl.N\C(=N/OCC(O)CN1CCCCC1)c2cccnc2

InChI

1S/C14H22N4O2.2ClH/c15-14(12-5-4-6-16-9-12)17-20-11-13(19)10-18-7-2-1-3-8-18;;/h4-6,9,13,19H,1-3,7-8,10-11H2,(H2,15,17);2*1H

InChI key

ISGGVCWFTPTHIX-UHFFFAOYSA-N

General description

BGP-15 is a hydroxylamine derivative, which has cytoprotective and neuroprotective properties. It reduces phospho- c-Jun N-terminal kinase (pJNK) and p38 stress signalling. BGP-15 also stimulates non-specific serine/threonine protein kinase (AKT) and insulin-like growth factor 1 receptor (IGFR1) protective signalling. BGP-15 functions as an insulin sensitizer in an olanzapine-induced metabolic disorder. It protects cells against cell death and enhances the expression of heat shock protein (HSP). BGP-15 might be used to treat heart failure (HF) and atrial fibrillation (AF).[1]

Application

BGP-15 has been used to study its influence on proteasomal degradation of missense dystrophins.

Biochem/physiol Actions

BGP-15 is PARP inhibitor, HSP72 activator.
BGP-15 is PARP inhibitor, HSP72 activator.

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This Item
C8874565840S5451
BGP-15 ≥98% (HPLC)

Sigma-Aldrich

B4813

BGP-15

CGP-37157 ≥98% (HPLC), powder

Sigma-Aldrich

C8874

CGP-37157

SHIP2 Inhibitor, AS1938909 The SHIP2 Inhibitor, AS1938909 controls the biological activity of SHIP2. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

Sigma-Aldrich

565840

SHIP2 Inhibitor, AS1938909

Sarpogrelate hydrochloride ≥98% (HPLC)

Sigma-Aldrich

S5451

Sarpogrelate hydrochloride

form

solid

form

powder

form

solid

form

solid

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥95% (HPLC)

assay

≥98% (HPLC)

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

room temp

solubility

deionized water: 28 mg/mL

solubility

DMSO: ≥20 mg/mL

solubility

DMSO: 50 mg/mL

solubility

deionized water: ≥5 mg/mL

pictograms

Skull and crossbones
GHS06

signalword

Danger

hcodes

H301

Hazard Classifications

Acute Tox. 3 Oral

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
0000201999
0000201999
0000140274
0000123636
0000123637

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Global Trade Item Number

SKUGTIN
B4813-25MG04061833217580
B4813-5MG04061833217597

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