A4284

L-Asparagine monohydrate

BioReagent, suitable for cell culture

• Synonym(s): (S)-(+)-2-Aminosuccinamic acid, (S)-2-Aminosuccinic acid 4-amide, L-Aspartic acid 4-amide
• Linear Formula: NH₂COCH₂CH(NH₂)COOH · H₂O
• CAS Number: 5794-13-8
• Molecular Weight: 150.13
• UNSPSC Code: 12352209
• NACRES: NA.75
• PubChem Substance ID: 24890843
• EC Number: 200-735-9
• Beilstein/REAXYS Number: 1723527
• MDL number: MFCD00151038

Properties

• biological source: synthetic
• Quality Segment: 300
• product line: BioReagent
• assay: ≥99% (TLC)
• form: powder
• technique(s): cell culture | mammalian: suitable
• color: white to off-white
• mp: 233-235 °C (lit.)
• SMILES string: [H]O[H].N[C@@H](CC(N)=O)C(O)=O
• InChI: 1S/C4H8N2O3.H2O/c5-2(4(8)9)1-3(6)7;/h2H,1,5H2,(H2,6,7)(H,8,9);1H2/t2-;/m0./s1
• InChI key: RBMGJIZCEWRQES-DKWTVANSSA-N

Description

Application

L-Asparagine monohydrate has been used:

• as a media supplement to culture Black Mexican Sweet (BMS) cells[1]
• to prepare Adams III media to supplement C+Y medium for culturing Streptococcus pneumoniae[2]
• in an asparagine-rich diet to study the E0771 syngeneic breast tumor growth and survival in mice[3]

Biochem/physiol Actions

L-Asparagine (L-Asp) is a nonessential amino acid involved in the synthesis of critical cellular proteins of human cells. It is synthesized from oxaloacetic acid. L-Asp is used as a growth supplement for tumor cells in in vitro conditions.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)