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54880

3-Hydroxybenzylhydrazine dihydrochloride

≥98.0% (HPLC)

Synonym(s):

α-Hydrazino-m-cresol dihydrochloride, 3-(Hydrazinomethyl)phenol dihydrochloride, NSD-1015

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Pack SizeSKUAvailabilityPrice
1 g

Available to ship TODAYfromMILWAUKEE

$262.00
$222.70

About This Item

Linear Formula:
HOC6H4CH2NHNH2 · 2HCl
CAS Number:
81012-99-9
Molecular Weight:
211.09
UNSPSC Code:
12352202
NACRES:
NA.77
PubChem Substance ID:
24878937
EC Number:
279-659-3
Beilstein/REAXYS Number:
9282965
MDL number:
MFCD00044695
Assay:
≥98.0% (HPLC)
Form:
solid
Quality level:
100

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Quality Level

100

assay

≥98.0% (HPLC)

form

solid

mp

137-140 °C, 138-140 °C (lit.)

solubility

H2O: 50 mg/mL, slightly hazy, faintly yellow

SMILES string

Cl[H].Cl[H].NNCc1cccc(O)c1

InChI

1S/C7H10N2O.2ClH/c8-9-5-6-2-1-3-7(10)4-6;;/h1-4,9-10H,5,8H2;2*1H

InChI key

ONOJPUDFIOEGCX-UHFFFAOYSA-N

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1 of 1

This Item
H139B4563SML0635
3-Hydroxybenzylhydrazine dihydrochloride ≥98.0% (HPLC)

Sigma-Aldrich

54880

3-Hydroxybenzylhydrazine dihydrochloride

HA-1077 dihydrochloride solid, ≥98% (HPLC)

Sigma-Aldrich

H139

HA-1077 dihydrochloride

Bisantrene dihydrochloride ≥98% (HPLC)

Sigma-Aldrich

B4563

Bisantrene dihydrochloride

AZD6765 dihydrochloride ≥97% (HPLC)

Sigma-Aldrich

SML0635

AZD6765 dihydrochloride

assay

≥98.0% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥97% (HPLC)

form

solid

form

solid

form

solid

form

powder

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

solubility

H2O: 50 mg/mL, slightly hazy, faintly yellow

solubility

H2O: >10 mg/mL

solubility

deionized water: 8 mg/mL

solubility

H2O: 20 mg/mL, clear

mp

137-140 °C, 138-140 °C (lit.)

mp

-

mp

-

mp

-

Biochem/physiol Actions

Inhibitor of L-aromatic amino acid decarboxylase; crosses blood brain barrier.
Inhibitor of L-aromatic amino acid decarboxylase; crosses blood brain barrier. Also inhibits GABA aminotransferase, as well as other pyridoxal-phosphate-requiring enzymes, by forming the 3-hydroxybenzylhydrazone of that cofactor.

pictograms

CorrosionExclamation mark
GHS05,GHS07

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCBT7147
BCBG5065V
BCBB1136V
BCBB1136
1445429

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Translational psychiatry, 2, e122-e122 (2012-07-27)
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Gerard Honig et al.
PloS one, 4(8), e6797-e6797 (2009-08-28)
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Noriko Wakabayashi-Ito et al.
PloS one, 6(10), e26183-e26183 (2011-10-25)
Dystonia represents the third most common movement disorder in humans. At least 15 genetic loci (DYT1-15) have been identified and some of these genes have been cloned. TOR1A (formally DYT1), the gene responsible for the most common primary hereditary dystonia
Adrian M Russo et al.
Behavioural brain research, 359, 918-926 (2018-06-24)
Autism spectrum disorder (ASD) is a heterogeneous and highly heritable condition with multiple aetiologies. Although the biological mechanisms underlying ASD are not fully understood, evidence suggests that dysregulation of serotonergic systems play an important role in ASD psychopathology. Preclinical models
Anees A Banday et al.
American journal of physiology. Renal physiology, 317(4), F949-F956 (2019-08-15)
The role of dopamine D1-like receptors (DR) in the regulation of renal Na+ transporters, natriuresis, and blood pressure is well established. However, the involvement of the angiotensin 1-7 (ANG 1-7)-Mas receptor in the regulation of Na+ balance and blood pressure
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Global Trade Item Number

SKUGTIN
54880-1G-F04061832574912
54880-5G-F04061833021781

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