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06863

Glycoursodeoxycholic acid

≥96.0% (TLC)

Synonym(s):

N-(3α,7β-Dihydroxy-5β-cholan-24-oyl)glycine, N-[(3α,5β,7β)-3,7-Dihydroxy-24-oxocholan-24-yl]glycine, GUDCA, Glycylursodeoxycholic acid, Ursodeoxycholylglycine

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Pack SizeSKUAvailabilityPrice
1 g

Available to ship TODAYfromMILWAUKEE

$407.00

About This Item

Empirical Formula (Hill Notation):
C26H43NO5
CAS Number:
Molecular Weight:
449.62
UNSPSC Code:
12161900
PubChem Substance ID:
NACRES:
NA.25
MDL number:

$407.00


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biological source

synthetic

Quality Segment

assay

≥96.0% (TLC)

form

powder

functional group

carboxylic acid

InChI

1S/C26H43NO5/c1-15(4-7-22(30)27-14-23(31)32)18-5-6-19-24-20(9-11-26(18,19)3)25(2)10-8-17(28)12-16(25)13-21(24)29/h15-21,24,28-29H,4-14H2,1-3H3,(H,27,30)(H,31,32)/t15-,16+,17-,18-,19+,20+,21+,24+,25+,26-/m1/s1

InChI key

GHCZAUBVMUEKKP-XROMFQGDSA-N

Application


  • Glycoursodeoxycholic Acid Alleviates Arterial Thrombosis via Suppressing Diacylglycerol Kinases Activity in Platelet.: Highlights the therapeutic potential of Glycoursodeoxycholic acid in alleviating arterial thrombosis by inhibiting diacylglycerol kinase activity in platelets (Yang et al., 2024).

Biochem/physiol Actions

Secondary bile acid derived from acyl glycine. Glycoursodeoxycholic Acid (GUDCA) is reported to have cytoprotective and anti-inflammatory effects.

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This Item
U5127G2878H3878
form

powder

form

powder

form

powder

form

-

assay

≥96.0% (TLC)

assay

≥99%

assay

≥97% (HPLC)

assay

≥98%

biological source

synthetic

biological source

-

biological source

synthetic

biological source

-

Quality Level

100

Quality Level

200

Quality Level

200

Quality Level

200

functional group

carboxylic acid

functional group

-

functional group

amide

functional group

-


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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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Protocols

Investigate bile acid roles in gut hormone profiles and glycemic control, vital for clinical labs exploring potential mechanisms.

Related Content

Bile Acids (BA) are synthesized in the liver and play important roles in cholesterol homeostasis, absorption of vitamins and lipids, and various key metabolic processes.


A Roda et al.
Pharmaceutical research, 11(5), 642-647 (1994-05-01)
A new enteric-coated formulation of sodium ursodeoxycholate was prepared and administered to man. The barrier film disintegrates and releases the drug only at pH > or = 5.5. The sodium salt of glycoursodeoxycholate was also prepared and encapsulated like ursodeoxycholate.
A Roda et al.
The Journal of biological chemistry, 258(10), 6362-6370 (1983-05-25)
The relationship between chemical structure and the concentration at which self-association occurs in water or in 0.15 M Na+ ion was examined for more than 50 bile salts and bile salt analogues varying in substituents on the steroid nucleus or
Ewa Ellis et al.
Hepatology (Baltimore, Md.), 38(4), 930-938 (2003-09-27)
Primary human hepatocytes were used to elucidate the effect of individual bile acids on bile acid formation in human liver. Hepatocytes were treated with free as well as glycine-conjugated bile acids. Bile acid formation and messenger RNA (mRNA) levels of



Global Trade Item Number

SKUGTIN
06863-1G04061826268872

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