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03394

Poly(ethylene glycol)

greener alternative

tested according to Ph. Eur., 6,000

Synonym(s):

PEG, Macrogol 6,000, Polyethylene glycol

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1 kg
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$115.00
$86.25

About This Item

Linear Formula:
H(OCH2CH2)nOH
CAS Number:
25322-68-3
NACRES:
NA.21
PubChem Substance ID:
24845475
UNSPSC Code:
12352104
MDL number:
MFCD00081839

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agency

tested according to Ph. Eur.

Quality Segment

200

form

solid

mol wt

5000-7000

greener alternative product characteristics

Safer Solvents and Auxiliaries
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

solubility

aliphatic hydrocarbons: slightly soluble, organic solvents: soluble

application(s)

pharmaceutical (small molecule)

greener alternative category

Aligned

InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

InChI key

LYCAIKOWRPUZTN-UHFFFAOYSA-N

General description

We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Green Chemistry. Polyethylene glycol (PEG) is an eco-friendly, biodegradable polymer widely used in pharmaceuticals and cosmetics. Its non-toxic nature and versatility make it a sustainable choice, derived from renewable resources, contributing to greener product formulations. Click here for more information.

Application

Poly(ethylene glycol) was used as hydrophilic carriers for characterizing the sirolimus solid dispersion nanoparticles.[1]

Biochem/physiol Actions

Polyethylene glycol (PEG) is a condensation polymer of ethylene oxide and water. It enhances the refolding of extracted proteins. This enables characterization of crystallized proteins.[2][3]

Preparation Note

Poly(ethylene glycol) dissolves in many organic solvents and is readily soluble in aromatic hydrocarbons. It also slightly dissolves in aliphatic hydrocarbons.

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Poly(ethylene glycol)

form

solid

form

liquid

form

-

form

-

Quality Level

200

Quality Level

200

Quality Level

100

Quality Level

100

mol wt

5000-7000

mol wt

380-420

mol wt

Mn ~900, Mp ~970, Mw ~940

mol wt

Mn ~550, Mp ~600, Mw ~580

agency

tested according to Ph. Eur.

agency

tested according to Ph. Eur.

agency

-

agency

-

greener alternative category

Aligned

greener alternative category

Aligned

greener alternative category

Aligned

greener alternative category

Aligned

sustainability

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sustainability

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sustainability

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Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
BCCN6664
BCCM5872
BCCL7063
BCCK9508
BCCJ9479

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J L Cleland et al.
The Journal of biological chemistry, 267(19), 13327-13334 (1992-07-05)
Polyethylene glycol (PEG) inhibited aggregation during refolding of bovine carbonic anhydrase B (CAB) through the formation of a nonassociating PEG-intermediate complex. Stoichiometric concentrations of PEG were required for complete recovery of active protein during refolding at aggregating conditions. For example
J L Cleland et al.
Bio/technology (Nature Publishing Company), 10(9), 1013-1019 (1992-09-01)
Previous studies on the refolding of recombinant bovine carbonic anhydrase B (CAB) indicated that polyethylene glycol (PEG) significantly enhanced the recovery of active protein by reducing aggregation. To further test the ability of PEG to enhance refolding, three recombinant human
Min-Soo Kim et al.
International journal of nanomedicine, 6, 2997-3009 (2011-12-14)
The aim of this study was to improve the physicochemical properties and bioavailability of poorly water-soluble sirolimus via preparation of a solid dispersion of nanoparticles using a supercritical antisolvent (SAS) process. First, excipients for enhancing the stability and solubility of
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Global Trade Item Number

SKUGTIN
206253-1G04061826741061
03394-1KG04061838618443

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