AB5684

Anti-Neurogenin-3 Antibody, a.a. 80-93 of mouse Neurogenin-3.

Chemicon^®, from rabbit

• Synonym(s): MATH4b
• UNSPSC Code: 12352203
• NACRES: NA.41
• eCl@ss: 32160702
• Conjugate: unconjugated
• Clone: polyclonal
• Application: IHC
• Citations: 10

Properties

• biological source: rabbit
• Quality Segment: 100
• conjugate: unconjugated
• antibody form: affinity purified immunoglobulin
• antibody product type: primary antibodies
• clone: polyclonal
• purified by: affinity chromatography
• species reactivity: human, rat, mouse
• manufacturer/tradename: Chemicon^®
• technique(s): immunohistochemistry: suitable
• isotype: IgG
• NCBI accession no.: NM_020999.2
• UniProt accession no.: Q9Y4Z2
• shipped in: dry ice
• target post-translational modification: unmodified
• Gene Information: human ... NEUROG3(50674)

Description

General description

Neurogenins are a family of bHLH transcription factors involved in specifying neuronal differentiation. They are related to Drosophila atonal. The neurogenins (ngns) make up one of these atonal-related gene families. In neural crest cells, the atonal-related neurogenin family is particularly important for the sensory lineage (Neurogenins Are Essential for the Formation of dorsal root ganglia), while the achaete-scute homologue ash1 (Mash1) is important for aspects of autonomic neurogenesis (Mash1 Is Essential for Noradrenergic Differentiation). Neurogenin-3 promotes pancreatic development.

~ 23 kDa

Immunogen

Epitope: a.a. 80-93 of mouse Neurogenin 3.

Synthetic peptide, amino acids 80-93 of mouse Neurogenin 3.

Application

Anti-Neurogenin-3 Antibody, a.a. 80-93 of mouse Neurogenin-3. detects level of Neurogenin-3 & has been published & validated for use in IH.

Immunohistochemistry: 1:200-1:1,000.
Immunocytochemistry: Cat. # AB5684 detects Neurogenin-3 in PC12 cells at 1:500 dilution.
Not recommended for Western blot

Research Category
Neuroscience

Research Sub Category
Developmental Neuroscience

Neuronal & Glial Markers

Biochem/physiol Actions

Recognizes Neurogenin 3 (MATH4b), a Helix-loop-helix class of transcription factor.

Physical form

Affinity purified immunoglobulin. Precipitated antibody in a solution of 50% saturated ammonium sulfate and PBS containing no preservatives.

Preparation Note

Stable for 1 year at -20ºC from date of receipt.

Analysis Note

Control
Rat brain tissue.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class: 12 - Non Combustible Liquids
• wgk: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable