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For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf
8.04518
N-Hydroxysuccinimide
≥99.0% (acidimetric), for peptide synthesis
Synonym(s):
N-Hydroxysuccinimide, 1-Hydroxy-2,5-pyrrolidinedione
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 25 g | Check Cart for Availability | $51.70 | |
| 100 g | Check Cart for Availability | $156.00 | |
| 500 g | Check Cart for Availability | $505.00 |
About This Item
Product Name
N-Hydroxysuccinimide, for synthesis
Quality Segment
assay
≥99.0% (acidimetric)
form
crystals
reaction suitability
reaction type: Addition Reactions
pH
5-7 (20 °C, 50 g/L in H2O)
mp
93-100 °C
application(s)
peptide synthesis
SMILES string
N1(C(=O)CCC1=O)O
InChI
1S/C4H5NO3/c6-3-1-2-4(7)5(3)8/h8H,1-2H2
InChI key
NQTADLQHYWFPDB-UHFFFAOYSA-N
Application
- Direct Cα-heteroarylation of structurally diverse ethers: This study showcases a mild N-hydroxysuccinimide mediated cross-dehydrogenative coupling reaction, expanding the utility of NHS in organic synthesis. (Liu et al., 2017).
Analysis Note
Melting range (lower value): ≥ 95 °C
Melting range (upper value): ≤ 100 °C
Identity (IR): passes test
1 of 1
This Item | |||
|---|---|---|---|
| form crystals | form solid | form solid | form solid |
| assay ≥99.0% (acidimetric) | assay 98% | assay ≥97.0% (T) | assay 96% |
| Quality Level 200 | Quality Level 200 | Quality Level 200 | Quality Level 100 |
| mp 93-100 °C | mp 95-98 °C (lit.) | mp 95-98 °C | mp 136-138 °C |
| application(s) peptide synthesis | application(s) - | application(s) peptide synthesis | application(s) - |
| reaction suitability reaction type: Addition Reactions | reaction suitability - | reaction suitability reaction type: Addition Reactions | reaction suitability - |
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signalword
Danger
hcodes
Hazard Classifications
Eye Dam. 1 - Skin Irrit. 2
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Global Trade Item Number
| SKU | GTIN |
|---|---|
| 8045180025 | 04022536385167 |
| 8045180100 | 04022536731162 |
| 8045189999 | 04022536385174 |
| 8045180500 | 04022536764672 |
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How is shipping temperature determined? And how is it related to the product storage temperature?
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Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
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