8.02809

2-Chloropropane

for synthesis

• Synonym(s): 2-Chloropropane, Isopropyl chloride
• Linear Formula: (CH₃)₂CHCl
• CAS Number: 75-29-6
• Molecular Weight: 78.54
• UNSPSC Code: 12352101
• EC Index Number: 200-858-8
• NACRES: NA.22
• MDL number: MFCD00000867
• Form: liquid

Properties

• vapor pressure: 592.1 hPa ( 20 °C)
• Quality Segment: 200
• form: liquid
• autoignition temp.: 590 °C
• potency: >2000 mg/kg LD₅₀, oral (Rat), >2000 mg/kg LD₅₀, skin (Rabbit)
• expl. lim.: 2.8-10.7 % (v/v)
• mp: -118 °C
• transition temp: flash point -36 °C
• density: 0.86 g/cm³ at 20 °C
• storage temp.: 2-30°C
• SMILES string: ClC(C)C
• InChI: 1S/C3H7Cl/c1-3(2)4/h3H,1-2H3
• InChI key: ULYZAYCEDJDHCC-UHFFFAOYSA-N

Description

Application

• Development and validation of Genotoxic Impurities Chloromethane, Chloroethane and 2-Chloropropane, in Pregabalin drug substance using Head-Space: This study focuses on the detection and quantification of 2-Chloropropane as a genotoxic impurity in pharmaceutical products using head-space gas chromatography (P Bharath, PVS Gupta, SM Ali, D Ramachandran).
• Photocatalytic breakdown of 2-chloropropane: Research on the effectiveness of a photocatalytic reactor designed for the degradation of 2-Chloropropane in environmental applications (EC Ajiduku, E Kamba, R Odoh, 2023).
• Density and speed of sound of 2-chloropropane: An exploration into the physical properties of 2-Chloropropane under various temperatures and pressures, providing valuable data for industrial and laboratory applications (VV Melent′ev, EB Postnikov, 2019).
• Theoretic studies on the kinetics and mechanism of multi-channel gas-phase unimolecular reactions of 1-chloropropane and 2-chloropropane: Theoretical analysis providing insights into the thermal decomposition pathways of 2-Chloropropane, important for understanding its stability and reactivity (V Saheb, 2014).

Safety Information

• pictograms: GHS02,GHS07
• signalword: Danger
• pcodes: P210 - P233 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P312
• Hazard Classifications: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Flam. Liq. 2
• Storage Class: 3 - Flammable liquids
• wgk: WGK 1
• flash_point_f: -32.8 °F
• flash_point_c: -36 °C
• hcodes: H225,H302 + H312 + H332