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218840

Caspase-8 Inhibitor II

InSolution

Synonym(s):

InSolution Caspase-8 Inhibitor II, Granzyme B Inhibitor III; Z-IE(OMe)TD(OMe)-FMK

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Pack SizeSKUAvailabilityPrice
250 μg
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$161.00

About This Item

Empirical Formula (Hill Notation):
C30H43FN4O11
Molecular Weight:
654.68
NACRES:
NA.54
UNSPSC Code:
12352200
Form:
liquid
Quality level:
100
Storage condition:
OK to freeze, desiccated (hygroscopic), protect from light

$161.00

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Quality Level

100

form

liquid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze, desiccated (hygroscopic), protect from light

shipped in

wet ice

storage temp.

−20°C

General description

A 5 mM (250 µg/76 µl) solution of Z-IETD-FMK (Cat. No. 218759) in DMSO. Z-IETD-FMK is a potent, cell-permeable, and irreversible inhibitor of caspase-8 (MACH, FLICE, Mch5). Also inhibits granzyme B.

Biochem/physiol Actions

Cell permeable: yes
Primary Target
caspase-8
Product does not compete with ATP.
Reversible: no

Packaging

Packaged under inert gas

Physical form

A 5 mM (250 µg/76 µl) solution of Z-IETD-FMK (Cat. No. 218759) in DMSO.

Preparation Note

Following initial thaw, aliquot and freeze (-20°C).

Analysis Note

≥98% (HPLC)

Other Notes

Martin, D.A., et al. 1998. J. Biol. Chem.273, 4345.
Sweeney, E.A., et al. 1998. FEBS Lett.425, 61.
Z-Ile-Glu(OMe)-Thr-Asp(OMe)-CH₂F*

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Irritant (B)

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This Item
218753264155218773
Caspase-8 Inhibitor II InSolution

Sigma-Aldrich

218840

Caspase-8 Inhibitor II

Caspase-5 Inhibitor I Z-WEHD-FMK is a cell-permeable, potent, irreversible caspase-5 inhibitor, that also inhibits the activity of Caspase 1, 4, and 8.

Sigma-Aldrich

218753

Caspase-5 Inhibitor I

Caspase-3 Inhibitor II The Caspase-3 Inhibitor II, also referenced under CAS 210344-95-9, controls the biological activity of Caspase-3. This small molecule/inhibitor is primarily used for Cancer applications.

Sigma-Aldrich

264155

Caspase-3 Inhibitor II

Caspase-8 Inhibitor I, Cell-Permeable The Caspase 8 Inhibitor I, Cell-Permeable controls the biological activity of Caspase-8. This small molecule/inhibitor is primarily used for Cancer applications.

Sigma-Aldrich

218773

Caspase-8 Inhibitor I, Cell-Permeable

form

liquid

form

solid

form

solid

form

lyophilized solid

Quality Level

100

Quality Level

100

Quality Level

200

Quality Level

100

manufacturer/tradename

Calbiochem®

manufacturer/tradename

Calbiochem®

manufacturer/tradename

Calbiochem®

manufacturer/tradename

Calbiochem®

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage condition

OK to freeze, protect from light, desiccated (hygroscopic)

storage condition

OK to freeze, desiccated

storage condition

OK to freeze, desiccated

storage condition

OK to freeze

shipped in

wet ice

shipped in

ambient

shipped in

ambient

shipped in

ambient

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Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

188.6 °F - (refers to pure substance)

flash_point_c

87 °C - (refers to pure substance)

Certificates of Analysis (COA)

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Global Trade Item Number

SKUGTIN
218840-250UG04055977218923

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