1.06444

Sodium chloride

EMPROVE^® API Ph Eur,BP,JP,USP

• Synonym(s): Halite, NaCl
• Linear Formula: NaCl
• CAS Number: 7647-14-5
• Molecular Weight: 58.44
• Beilstein/REAXYS Number: 3534976
• MDL number: MFCD00003477
• UNSPSC Code: 12352302
• EC Index Number: 231-598-3

Properties

• agency: BP; JP; Ph. Eur.; USP
• Quality Level: 600
• vapor pressure: 1.3 hPa ( 865 °C)
• product line: EMPROVE^® API
• form: solid
• potency: 3000 mg/kg LD₅₀, oral (Rat); >10000 mg/kg LD₅₀, skin (Rabbit)
• pH: 4.5-7.0 (20 °C, 100 g/L in H₂O)
• bp: 1461 °C
• mp: 801 °C (lit.)
• solubility: 358 g/L
• bulk density: 1140 kg/m³
• application(s): liquid formulation; ophthalmics; parenterals; pharmaceutical; semi-solid formulation; solid formulation
• storage temp.: 2-25°C
• SMILES string: [Na+].[Cl-]
• InChI: 1S/ClH.Na/h1H;/q;+1/p-1
• InChI key: FAPWRFPIFSIZLT-UHFFFAOYSA-M

Description

General description

We provide industry-leading production know-how and comprehensive regulatory support for high-quality APIs, backed by nearly 200 years of experience. From a complete portfolio of innovative folates to custom synthesis, our customized and scalable solutions meet your specific production needs. As part of our EMPROVE^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Sodium chloride is used in ophthalmic, dialysis, clinical nutrition and infusion solutions. Sodium chloride Emprove^® API is manufactured according to ICH Q7 guidelines. A CEP is available.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class: 13 - Non Combustible Solids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable