Skip to Content
MilliporeSigma
All Photos(1)

Documents

07-790

Sigma-Aldrich

Anti-phospho-PKCα (Ser657/Tyr658) Antibody

Upstate®, from rabbit

Synonym(s):

PRKCA, PKC-alpha, PKCA, PRKACA

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

100

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

human, rat, rabbit

manufacturer/tradename

Upstate®

technique(s)

ELISA: suitable
immunoprecipitation (IP): suitable
western blot: suitable

isotype

IgG

NCBI accession no.

NM_002737.2

UniProt accession no.

P17252

shipped in

dry ice

Gene Information

human ... PRKCA(5578)

Specificity

Recognizes phospho-PKCα (Ser657/Tyr658). This sequence is similar to PKCβI (Ser661/Tyr662) and PKCγ (Thr674/Tyr675).

Immunogen

KLH conjugated peptide corresponding to amino acid region encompassing the human phospho-PKCα (Ser657/Tyr658).

Application

Anti-phospho-PKCα (Ser657/Tyr658) Antibody detects level of phospho-PKCα (Ser657/Tyr658) & has been published & validated for use in ELISA, IP & WB.
Research Category
Metabolism
Research Sub Category
Enzymes & Biochemistry

Quality

Routinely evaluated by immunoblot.

Target description

82 kDa

Physical form

ImmunoAffinity Purified

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Not finding the right product?  

Try our Product Selector Tool.

Storage Class

12 - Non Combustible Liquids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Phosphorylated HSP27 modulates the association of phosphorylated caldesmon with tropomyosin in colonic smooth muscle
Somara, Sita and Bitar, Khalil N
American Journal of Physiology: Gastrointestinal and Liver Physiology, 291, G630-G639 (2006)
Samantha J Borland et al.
Cardiovascular research, 113(13), 1639-1652 (2017-10-11)
Vascular calcification is a major cause of morbidity and mortality. Fibroblast growth factor-2 (FGF-2) plays an instructive role in osteogenesis and bone development, but its role in vascular calcification was unknown. Therefore, we investigated the involvement of FGF-2 in vascular
Zangbéwendé Guy Ouédraogo et al.
Brain pathology (Zurich, Switzerland), 26(1), 18-30 (2015-03-05)
Radiotherapy is an essential component of glioma standard treatment. Glioblastomas (GBM), however, display an important radioresistance leading to tumor recurrence. To improve patient prognosis, there is a need to radiosensitize GBM cells and to circumvent the mechanisms of resistance caused
Haoran Miao et al.
Oncology reports, 48(6) (2022-10-26)
Current investigations suggest that pigment epithelial‑derived factor (PEDF) can mediate the progression of non‑small cell lung cancer (NSCLC) by regulating autophagy. However, the underlying mechanisms associated with autophagy remain poorly elucidated. The aim of the present study was to investigate
Moona Huttunen et al.
Cellular microbiology, 19(3) (2016-10-21)
We have demonstrated previously that the human picornavirus Echovirus 1 (EV1) triggers an infectious internalization pathway that follows closely, but seems to stay separate, from the epidermal growth factor receptor (EGFR) pathway triggered by epidermal growth factor (EGF). Here, we
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service