GPR62 constitutively activates cAMP signaling but is dispensable for male fertility in mice.

GPR62 constitutively activates cAMP signaling but is dispensable for male fertility in mice.

Reproduction (Cambridge, England) (2017-09-16)

Tomoyuki Muroi, Yuri Matsushima, Ryota Kanamori, Hikari Inoue, Wataru Fujii, Keiichiro Yogo

ABSTRAKT

G-protein-coupled receptors (GPCRs) participate in diverse physiological functions and are promising targets for drug discovery. However, there are still over 140 orphan GPCRs whose functions remain to be elucidated.

MATERIAŁY

Numer produktu

Marka

Opis produktu

D5796

Sigma-Aldrich

Dulbecco′s Modified Eagle′s Medium - high glucose, With 4500 mg/L glucose, L-glutamine, and sodium bicarbonate, without sodium pyruvate, liquid, sterile-filtered, suitable for cell culture

A5955

Sigma-Aldrich

Antibiotic Antimycotic Solution (100×), Stabilized, with 10,000 units penicillin, 10 mg streptomycin and 25 μg amphotericin B per mL, 0.1 μm filtered, BioReagent, suitable for cell culture