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Merck

Immobilization of enzymes on a microchannel surface through cross-linking polymerization.

Chemical communications (Cambridge, England) (2005-10-13)
Takeshi Honda, Masaya Miyazaki, Hiroyuki Nakamura, Hideaki Maeda
ABSTRAKT

A novel and facile method for the preparation of an enzyme-immobilized microreactor has been developed in which enzymes are immobilized as an enzyme-polymer membrane formed on the inner wall of the microchannel by a cross-linking polymerization method; the resulting microreactor shows excellent reaction performance and stability against denaturating agents.

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Sigma-Aldrich
N-Glutaryl-L-phenylalanine p-nitroanilide, protease substrate