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1592409

USP

Quercetin

United States Pharmacopeia (USP) Reference Standard

Synonim(y):

Quercetin dihydrate, 2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxy-4H-1-benzopyran-4-one dihydrate, 3,3′,4′,5,7-Pentahydroxyflavone dihydrate

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About This Item

Wzór empiryczny (zapis Hilla):
C15H10O7 · 2H2O
Numer CAS:
6151-25-3
Masa cząsteczkowa:
338.27
Numer w indeksie barw:
75670
Beilstein:
317313
Numer MDL:
MFCD00149487
Kod UNSPSC:
41116107
NACRES:
NA.24

klasa czystości

pharmaceutical primary standard

rodzina API

quercetin

producent / nazwa handlowa

USP

mp

>300 °C (lit.)

Zastosowanie

pharmaceutical (small molecule)

Format

neat

temp. przechowywania

−20°C

ciąg SMILES

OC(C(O)=C1)=CC=C1C2=C(O)C(C3=C(O)C=C(O)C=C3O2)=O

InChI

1S/C15H10O7.2H2O/c16-7-4-10(19)12-11(5-7)22-15(14(21)13(12)20)6-1-2-8(17)9(18)3-6;;/h1-5,16-19,21H;2*1H2

Klucz InChI

GMGIWEZSKCNYSW-UHFFFAOYSA-N

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Opis ogólny

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Zastosowanie

Quercetin USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.
Also, for use with USP monographs such as:
  • Cranberry Fruit Juice Dry Extract
  • Japanese Sophora Flower
  • Japanese Sophora Flower Powder
  • Japanese Sophora Flower Bud
  • Japanese Sophora Flower Dry Extract
  • Cranberry Fruit Juice Dry Extract Capsules
  • Rutin

Działania biochem./fizjol.

Quercetin dihydrate is a flavonoid with anticancer activity. Quercetin is a mitochondrial ATPase and phosphodiesterase inhibitor. It Inhibits PI3-kinase activity and slightly inhibits PIP kinase activity. Quercetin has antiproliferative effects on cancer cell lines, reduces cancer cell growth via type II estrogen receptors, and arrests human leukemic T cells in late G1 phase of the cell cycle.

Komentarz do analizy

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Inne uwagi

Sales restrictions may apply.
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Opis
Cennik

Piktogramy

Skull and crossbones
GHS06

Hasło ostrzegawcze

Danger

Zwroty wskazujące rodzaj zagrożenia

H301,H315,H319

Klasyfikacja zagrożeń

Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2

Kod klasy składowania

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Klasa zagrożenia wodnego (WGK)

WGK 1

Wybierz jedną z najnowszych wersji:

Certyfikaty analizy (CoA)

Lot/Batch Number

Przepraszamy, ale COA dla tego produktu nie jest aktualnie dostępny online.

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Sigma-Aldrich

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Sigma-Aldrich

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Sigma-Aldrich

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Supelco

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Sigma-Aldrich

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Chronic inflammatory events appear to play a fundamental role in Alzheimer's disease (AD)-related neuropathological changes, and to result in neuronal dysfunction and death. The inflammatory responses observed in the AD brain include activation and proliferation of glial cells, together with
Catarina Cardoso et al.
PloS one, 9(8), e104201-e104201 (2014-08-16)
Strigolactones (SLs) trigger germination of parasitic plant seeds and hyphal branching of symbiotic arbuscular mycorrhizal (AM) fungi. There is extensive structural variation in SLs and plants usually produce blends of different SLs. The structural variation among natural SLs has been
Guozheng Huang et al.
European journal of medicinal chemistry, 81, 15-21 (2014-05-14)
Two sets of carbamates based on the natural alkaloid evodiamine were designed, synthesized and evaluated as potential butyrylcholinesterase inhibitors. Although a set of carbamates of 3-hydroxyevodiamine (10a-f) is inactive both at AChE and BChE, carbamates of 5-deoxo-3-hydroxyevodiamine (11a-f) exhibit much
Tomoaki Haraguchi et al.
Journal of agricultural and food chemistry, 62(24), 5589-5594 (2014-05-27)
This study demonstrated that 0.5% dietary rutin, ellagic acid, or curcumin markedly increased cecal succinate levels in rats fed a high-fat diet, whereas catechin, caffeic acid, and quercetin did not. Other organic acids were modestly or hardly affected by polyphenols.
Zhenghao Wu et al.
European journal of nutrition, 53(8), 1669-1683 (2014-02-27)
Maternal obesity is a risk factor for metabolic diseases in offspring. The aim of this study was to investigate whether quercetin administration during gestation and lactation could have any protective effect against the impact of maternal obesity on increased sensitivity
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Protokoły

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