V2390

VRT-532

≥98% (HPLC)

• Synonim(y): 4-Methyl-2-(5-phenyl-1H-pyrazol-3-yl)phenol, CFpot 532
• Wzór empiryczny (zapis Hilla): C₁₆H₁₄N₂O
• Numer CAS: 38214-71-0
• Masa cząsteczkowa: 250.30
• UNSPSC Code: 12352200
• Assay: ≥98% (HPLC)
• Form: solid

Właściwości

• InChI key: AQWKVJFRGORALM-UHFFFAOYSA-N
• InChI: 1S/C16H14N2O/c1-11-7-8-16(19)13(9-11)15-10-14(17-18-15)12-5-3-2-4-6-12/h2-10,19H,1H3,(H,17,18)
• assay: ≥98% (HPLC)
• form: solid
• solubility: DMSO: >20 mg/mL
• storage temp.: −20°C

Opis

Biochem/physiol Actions

VRT-532 is a mutated G551D CFTR corrector.

VRT-532 is a mutated G551D CFTR corrector. VRT-532 mediates G551D-CFTR by enhancement of ATP affinity of the mutant. VRT-532 also potentiates F508del mutated CFTR and works specifically on mutant CFTR rather than other membrane proteins.

Features and Benefits

This compound is featured on the Chloride Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

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Informacja o środkach bezpieczeństwa

• pictograms: GHS05,GHS07
• signalword: Danger
• hcodes: H302,H318
• pcodes: P280 - P301 + P312 + P330 - P305 + P351 + P338 + P310
• Hazard Classifications: Acute Tox. 4 Oral - Eye Dam. 1
• Klasa składowania: 11 - Combustible Solids
• wgk: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable