Ludzki JARID1A, znany również jako KDM5A i RBBP2, (GenBank Accession No. NM_001042603), aminokwasy 1-1090 z C-końcowym tagiem FLAG, MW = 125 kDa, wyrażany w komórkach Sf9 za pomocą systemu ekspresji Baculovirus.
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Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
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Chromosome rearrangements are found in many acute leukemias. As a result, genes at the breakpoints can be disrupted, forming fusion genes. One of the genes involved in several chromosome aberrations in hematological malignancies is NUP98 (11p15). As NUP98 is close
Histone H3 lysine 4 (H3K4) trimethylation (H3K4me3) at the promoter region of genes has been linked to transcriptional activation. In the present study, we found that hypoxia (1% oxygen) increased H3K4me3 in both normal human bronchial epithelial Beas-2B cells and
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 18(9), 1249-1257 (2005-04-02)
In malignant melanomas, the loss of cell cycle control is thought to be due to a lack of retinoblastoma protein (pRb)-activity. Members of the previously described family of retinoblastoma-binding proteins (RBPs) are supposed to act as pRb-modulating factors. Based on
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