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Informacje o tej pozycji
Wzór empiryczny (zapis Hilla):
C14H14INO2 · HCl
Numer CAS:
Masa cząsteczkowa:
391.63
NACRES:
NA.77
UNSPSC Code:
12352200
MDL number:
Pomoc techniczna
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Pozwól nam pomócNazwa produktu
T1AM, ≥98% (HPLC)
Quality Level
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
H2O: 10 mg/mL, clear
storage temp.
2-8°C
SMILES string
OC1=CC=C(OC2=C(I)C=C(CCN)C=C2)C=C1.[H]Cl
InChI
1S/C14H14INO2.ClH/c15-13-9-10(7-8-16)1-6-14(13)18-12-4-2-11(17)3-5-12;/h1-6,9,17H,7-8,16H2;1H
InChI key
RVKVVMXTPQCCIX-UHFFFAOYSA-N
Biochem/physiol Actions
3-iodothyronamine (T1AM) is present in vertebrate tissues and the circulatory system. Its physiological effects are the opposite of the thyroid hormone. T1AM acts as a neuromodulator as well as a hormone-like molecule.
T1AM (3-Iodothyronamine) is an endogenous biogenic amine derived from thyroid hormone.
T1AM (3-Iodothyronamine) is an endogenous biogenic amine derived from thyroid hormone. T1AM is a potent agonist of trace amine-associated receptor TAAR1 (TAR1, TA1), a GPCR primarily found in the brain.
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signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Klasa składowania
11 - Combustible Solids
wgk
WGK 3
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Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.
Carolin Stephanie Hoefig et al.
Thyroid : official journal of the American Thyroid Association, 26(12), 1656-1673 (2016-09-22)
Thyronamines (3-T
Annunziatina Laurino et al.
European journal of pharmacology, 793, 35-42 (2016-11-07)
3-iodothyronamine (T1AM) is a trace amine suspected to derive from thyroid hormone metabolism. T1AM was described as a ligand of G-protein coupled monoaminergic receptors, including trace amine associated receptors, suggesting the amine may exert a modulatory role on the monoaminergic
Muhammad Zahid Khan et al.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 83, 439-449 (2016-10-25)
Human trace amines (TAs) are endogenous compounds, previously almost ignored in human pathology for many reasons (difficulty of their measurement in biological fluids, unknown receptors for elusive amines), are now considered to play a significant role in synaptic transmission within
Numer pozycji handlu globalnego
| SKU | NUMER GTIN |
|---|---|
| SML1924-25MG | 04061832078014 |
| SML1924-5MG | 04061832078021 |

