SML1637

Hexaminolevulinate hydrochloride

≥98% (HPLC)

• Synonim(y): 5-Aminolevulinic acid hexyl ester HAL hydrochloride, 5-Aminolevulinic acid hexyl ester hydrochloride, HAL, Hexvix, Hexyl 5-aminolevulinate hydrochloride, P 1206, n-Hexyl 5-aminolevulinate hydrochloride
• Wzór empiryczny (zapis Hilla): C₁₁H₂₁NO₃ · HCl
• Numer CAS: 140898-91-5
• Masa cząsteczkowa: 251.75
• NACRES: NA.77
• PubChem Substance ID: 329825978
• UNSPSC Code: 12352200
• MDL number: MFCD03695491
• Assay: ≥98% (HPLC)
• Form: powder
• Storage condition: desiccated

Właściwości

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• storage condition: desiccated
• color: white to beige
• solubility: H₂O: 20 mg/mL, clear
• storage temp.: room temp
• SMILES string: CCCCCCOC(CCC(CN)=O)=O.[H]Cl
• InChI: 1S/C11H21NO3.ClH/c1-2-3-4-5-8-15-11(14)7-6-10(13)9-12;/h2-9,12H2,1H3;1H
• InChI key: LZYXPFZBAZTOCH-UHFFFAOYSA-N

Opis

Biochem/physiol Actions

Hexaminolevulinate (HAL) hydrochloride is a hexyl ester of 5-Aminolevulinic acid (ALA), a precursor to porphyrins including the photosensitizer protoporphyrin IX (PPIX). Hexaminolevulinate is more lipophilic than ALA, and is 50–100 times more efficient than ALA at inducing PpIX, which accumulates preferentially in neoplastic cells. Hexaminolevulinate administration followed by light activation has been used for fluorescence cystoscopy to enhance detection of bladder cancer, in particular carcinoma in situ (CIS). Hexaminolevulinate is also being studied for use in cancer photodynamic therapy. Hexaminolevulinate followed by irradiation produced DNA oxidative damage and apoptosis.

Hexaminolevulinate is a hexyl ester of 5-Aminolevulinic acid; imaging agen for fluorescence cyctoscopy; photosensitizer.

Ta strona może zawierać tekst przetłumaczony maszynowo.

Informacja o środkach bezpieczeństwa

• Klasa składowania: 11 - Combustible Solids
• wgk: WGK 3