SML0544

GRI977143

≥98% (HPLC)

• Synonim(y): 2-[[3-(1,3-Dioxo-1H-benz[de]isoquinolin-2(3H)-yl)propyl]thio]-benzoic acid
• Wzór empiryczny (zapis Hilla): C₂₂H₁₇NO₄S
• Numer CAS: 325850-81-5
• Masa cząsteczkowa: 391.44
• UNSPSC Code: 12352200
• NACRES: NA.77
• Assay: ≥98% (HPLC)
• Form: powder
• Quality level: 100

Właściwości

• SMILES string: S(CCC[n]2[c](c3c4c([c]2=O)cccc4ccc3)=O)c1c(cccc1)C(=O)O
• InChI: 1S/C22H17NO4S/c24-20-16-9-3-6-14-7-4-10-17(19(14)16)21(25)23(20)12-5-13-28-18-11-2-1-8-15(18)22(26)27/h1-4,6-11H,5,12-13H2,(H,26,27)
• InChI key: GMVZUCHUOYUMLL-UHFFFAOYSA-N
• assay: ≥98% (HPLC)
• form: powder
• color: white to light brown
• solubility: DMSO: 10 mg/mL, clear
• storage temp.: 2-8°C
• Quality Level: 100

Opis

Biochem/physiol Actions

GRI977143 is a potent, specific LPA2 receptor agonist with no affinity for other LPA receptors. GRI977143 inhibits the initiation of apoptosis induced by adriamycin or serum withdrawal in MEFs derived from LPA2 knock-out mice transfected with an LPA2 expression vector, but has no affect in non-transfected cells.

GRI977143 is a potent, specific LPA2 receptor agonist.

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Informacja o środkach bezpieczeństwa

• pictograms: GHS07,GHS09
• signalword: Warning
• hcodes: H302,H410
• pcodes: P264 - P270 - P273 - P301 + P312 - P391 - P501
• Hazard Classifications: Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1
• Klasa składowania: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable