SML0180

Aceclidine hydrochloride

≥98% (HPLC)

• Synonim(y): 1-Azabicyclo[2.2.2]oct-3-yl acetate hydrochloride, 3-Acetoxyquinuclidine hydrochloride
• Wzór empiryczny (zapis Hilla): C₉H₁₅NO₂ · HCl
• Numer CAS: 6109-70-2
• Masa cząsteczkowa: 205.68
• PubChem Substance ID: 329825209
• UNSPSC Code: 12352200
• NACRES: NA.77
• EC Number: 228-071-5
• Assay: ≥98% (HPLC)
• Form: powder
• Storage condition: desiccated

Właściwości

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• storage condition: desiccated
• color: white to tan
• solubility: H₂O: ≥15 mg/mL at ~60 °C
• storage temp.: −20°C
• SMILES string: Cl.CC(=O)O[C@H]1CN2CC[C@H]1CC2
• InChI: 1S/C9H15NO2.ClH/c1-7(11)12-9-6-10-4-2-8(9)3-5-10;/h8-9H,2-6H2,1H3;1H/t9-;/m0./s1
• InChI key: LWWSARSTZGNKGV-FVGYRXGTSA-N

Opis

Application

Aceclidine hydrochloride may be used in muscarinic acetylcholine receptor-mediated cell signaling studies.

Biochem/physiol Actions

Aceclidine hydrochloride is a parasympathomimetic drug with weak anticholinesterase activity. It acts on cholinergic nerve-endings, lowers intraocular pressure and potent therapeutic agent for open-angle glaucoma.[1]

Aceclidine is a non-selective muscarinic acetylcholine receptor partial agonist that is effective in reducing intraocular pressure.

Muscarinic receptor partial agonist

Aceclidine at a concentration of 5 and 50 μg is capable of enhancing the outflow facility, following ciliary muscle disinsertion.

Features and Benefits

This compound is featured on the Acetylcholine Receptors (Muscarinic) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

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Informacja o środkach bezpieczeństwa

• pictograms: GHS06
• signalword: Danger
• hcodes: H301 + H311
• pcodes: P264 - P280 - P301 + P310 - P302 + P352 + P312 - P361 + P364 - P405
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Oral
• Klasa składowania: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable