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SMB00607

Amoxicillin trihydrate: potassium clavulanate (4:1)

Synonim(y):

Amoxicillin Trihydrate: Potassium Clavulanate

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Rozmiar/SKUDostępnośćCena netto
1 g
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1310,00 zł

Informacje o tej pozycji

NACRES:
NA.85
UNSPSC Code:
51285005

1310,00 zł


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form

powder

Quality Segment

storage condition

(Keep container tightly closed in a dry and well-ventilated place. Never allow produc to get in contact with water during storage.)

color

white to yellow

antibiotic activity spectrum

Gram-negative bacteria, Gram-positive bacteria

mode of action

cell wall synthesis | interferes

storage temp.

2-8°C

General description

Amoxicillin trihydrate is a semisynthetic antibiotic, that is used as a medicine.

Application

Amoxicillin trihydrate: potassium clavulanate (4:1) has been used to study its effect on the viral déjà vu disease (neonatal intracerebral (i.c.) infection) in mice model.

Biochem/physiol Actions

Amoxicillin trihydrate is a broad-spectrum, β-lactam antibiotic. It inhibits the cross-linkage between linear peptidoglycan polymer chains that are the major component of both Gram-positive and Gram-negative bacteria. Since amoxicillin is degraded by β-lactamases, it does not show activity against bacteria which produce these enzymes.

Clavulanate is a β-lactam antibiotic related to the penicillins. Clavulanate competitively and irreversibly inhibits a wide variety of β-lactamases found in bacteria that are resistant to penicillins and cephalosporins.

Formulations of amoxicillin with clavulanic acid prevent the degradation of amoxicillin by β-lactamase enzymes. This increases amoxicillin′s antibacterial activity against bacteria normally resistant to β-lactam antibiotics.

Packaging

1G

Preparation Note

Keep container tightly closed in a dry and well-ventilated place. Never allow produc to get in contact with water during storage.

Other Notes

Keep container tightly closed in a dry and well-ventilated place. Never allow product to get in contact with water during storage.
Material is a powdered mixture of 4 parts amoxicillin trihydrate to 1 part potassium clavulanate.
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Ta pozycja
33454A852331586
description

-

description

VETRANAL®, analytical standard

description

95.0-102.0% anhydrous basis

description

VETRANAL®, analytical standard

antibiotic activity spectrum

Gram-positive bacteria, Gram-negative bacteria

antibiotic activity spectrum

-

antibiotic activity spectrum

Gram-positive bacteria, Gram-negative bacteria

antibiotic activity spectrum

-

mode of action

cell wall synthesis | interferes

mode of action

-

mode of action

cell wall synthesis | interferes

mode of action

-

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

100

form

powder

form

-

form

powder

form

-

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage condition

(Keep container tightly closed in a dry and well-ventilated place. Never allow produc to get in contact with water during storage.)

storage condition

-

storage condition

-

storage condition

-


Piktogramy

FlameHealth hazard

Słowo ostrzegawcze

Danger

Kody zagrożeń

Hazard Classifications

Flam. Sol. 2 - Resp. Sens. 1 - Self-heat. 2 - Skin Sens. 1

supp_hazards

Klasa składowania

4.2 - Pyrophoric and self-heating hazardous materials

Co się dzieje?

WGK 2

Temperatura zapłonu (°F)

Not applicable

Temperatura zapłonu (°C)

Not applicable



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Certyfikaty analizy (CoA)

Lot/Batch Number

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Questions

1–2 of 2 Questions  
  1. What is the solubility of Amoxicillin trihydrate: potassium clavulanate (4:1) (SMB00607)?

    1 answer
    1. This product is not tested for solubility. However, various literature sources note that the material is soluble at 1 mg/mL in water. Higher concentrations have been achieved with pH adjustment. Please see the link below to review a publication that may be helpful:
      https://pmc.ncbi.nlm.nih.gov/articles/PMC11440154/

      Helpful?

  2. What are the uses and potential reactions of Amoxicillin and Clavulanate Potassium

    1 answer
    1. This product is supplied for research purposes with the primary use as an antibiotic. Formulations of amoxicillin with clavulanic acid prevent the degradation of amoxicillin by β-lactamase enzymes. This increases amoxicillin's antibacterial activity against bacteria normally resistant to β-lactam antibiotics. Please see the peer-reviewed paper section in the link below for potential use information.

      https://www.sigmaaldrich.com/search/smb00607?focus=papers&page=1&perpage=30&sort=relevance&term=SMB00607&type=citation_search

      Products are not tested for safety and efficacy in food, drug, medical device, cosmetic, commercial, or any other use. Potential reactions or side effects are not evaluated.

      Helpful?

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