SAB4501954
Anti-HNRNP M antibody produced in rabbit
affinity isolated antibody
Synonim(y):
HNRPM, heterogeneous nuclear ribonucleoprotein M
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About This Item
Kod UNSPSC:
12352203
NACRES:
NA.41
pochodzenie biologiczne
rabbit
Poziom jakości
białko sprzężone
unconjugated
forma przeciwciała
affinity isolated antibody
rodzaj przeciwciała
primary antibodies
klon
polyclonal
Postać
buffered aqueous solution
masa cząsteczkowa
antigen 77 kDa
reaktywność gatunkowa
human, rat, mouse
stężenie
~1 mg/mL
metody
ELISA: 1:40000
immunofluorescence: 1:100-1:500
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
numer dostępu NCBI
numer dostępu UniProt
Warunki transportu
wet ice
temp. przechowywania
−20°C
informacje o genach
human ... HNRNPM(4670)
Opis ogólny
Anti-HNRNP M Antibody detects endogenous levels of total HNRNP M protein.
HNRNP M (heterogeneous nuclear ribonucleoprotein M) gene is mapped to human chromosome 19p13.2. It codes for a nucleocytoplasmic shuttling RNA binding protein.
Immunogen
The antiserum was produced against synthesized peptide derived from human hnRNP M.
Immunogen Range: 11-60
Immunogen Range: 11-60
Działania biochem./fizjol.
HnRNP M (heterogeneous nuclear ribonucleoprotein M) is an RNA binding protein and participates in mRNA splicing mechanism. It is significantly involved in the formation of mature mRNAs from heterogeneous nuclear RNAs. The encoded protein acts as an important gene expression regulating factor. HnRNPM is involved in the activation of IRES (internal ribosomal entry site)-dependent translation of FGF1 (fibroblast growth factor 1). Thus, this protein is associated with myoblast differentiation. HNRNP M expression is associated with the invasion and metastasis events of tumor cells. Upregulation of HNRNP M is observed in breast cancer and human colorectal epithelial carcinogenesis. Therefore, HnRNP M may serve as an important biomarker for cancer.
Cechy i korzyści
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Postać fizyczna
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Oświadczenie o zrzeczeniu się odpowiedzialności
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Kod klasy składowania
10 - Combustible liquids
Klasa zagrożenia wodnego (WGK)
nwg
Temperatura zapłonu (°F)
Not applicable
Temperatura zapłonu (°C)
Not applicable
Certyfikaty analizy (CoA)
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Masz już ten produkt?
Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.
Shuijiao Chen et al.
American journal of physiology. Gastrointestinal and liver physiology, 306(5), G394-G403 (2014-01-02)
Colorectal carcinoma (CRC) is one of the most common cancers in the world, and identification of new CRC biomarkers will be helpful for the diagnosis and treatment of CRC. For isobaric tags for relative and absolute quantitation (iTRAQ) analysis, fresh
Huizhi Sun et al.
Genes, chromosomes & cancer, 56(8), 598-607 (2017-04-11)
HnRNPM is an essential splicing factor and its expression is closely correlated with invasion and metastasis of tumor cells. The CD44 cell adhesion molecule is aberrantly expressed in many breast tumors and CD44 splice variants have been implicated in specific
Jacqueline Smith et al.
Mammalian genome : official journal of the International Mammalian Genome Society, 13(6), 310-315 (2002-07-13)
Human Chromosome 19 (HSA19) is virtually completely sequenced. A complete physical contig map made up of BACs and cosmids is also available for this chromosome. It is, therefore, a rich source of information that we have used as the basis
Nadera Ainaoui et al.
PloS one, 10(9), e0136466-e0136466 (2015-09-04)
Fibroblast growth factor 1 (FGF1) is induced during myoblast differentiation at both transcriptional and translational levels. Here, we identify hnRNPM and p54nrb/NONO present in protein complexes bound to the FGF1 promoter and to the mRNA internal ribosome entry site (IRES).
Julienne M Jagdeo et al.
Journal of virology, 89(14), 7064-7078 (2015-05-01)
Picornavirus infection involves a dynamic interplay of host and viral protein interactions that modulates cellular processes to facilitate virus infection and evade host antiviral defenses. Here, using a proteomics-based approach known as TAILS to identify protease-generated neo-N-terminal peptides, we identify
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