S8939

SGK1 (δ1-60, S422D), active human

recombinant, expressed in baculovirus infected Sf9 cells (truncated human sequence (a.a. 1-60 deleted, S422D mutation)-histidine-tagged), buffered aqueous solution

• Numer MDL: MFCD03458482
• Kod UNSPSC: 51111800
• NACRES: NA.32

Właściwości

• rekombinowane: expressed in baculovirus infected Sf9 cells (truncated human sequence (a.a. 1-60 deleted, S422D mutation)-histidine-tagged)
• Poziom jakości: 200
• Postać: buffered aqueous solution
• masa cząsteczkowa: ~48 kDa by SDS-PAGE
• numer dostępu UniProt: O00141
• Warunki transportu: dry ice
• temp. przechowywania: −70°C
• informacje o genach: human ... SGK1(6446)

Opis

Opis ogólny

The serum- and glucocorticoid-regulated kinase (SGK1) is a member of the AGC kinase family and the gene encoding it is localized on human chromosome 6q23.

Działania biochem./fizjol.

The serum- and glucocorticoid-regulated kinase (SGK1) has a role in the hormonal regulation of ion channels and pumps. It has been associated with cancers. The protein modulates nitric oxide production by activating NO synthase. SGK1 protects cells from apoptosis and oxidative stress.

Kinase assays.

Definicja jednostki

One unit of SGK1 = 1 nmol phosphate incorporated into crosstide substrate peptide in one minute.

Postać fizyczna

Solution in 50 mM Tris-HCl, pH 7.5, 0.1 mM EGTA, 0.1% β-mercaptoethanol, 0.15 M NaCl, 0.03% Brij^® L23, 1 mM benzamidine, 0.2 mM PMSF. and 270 mM sucrose.

Informacje prawne

Brij is a registered trademark of Croda International PLC

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 10 - Combustible liquids