For Sigma-Aldrich products where long-term storage is advised as freezer, our labels indicate -20C. Typically freezer facilities that are used to store these products are thermostatically temperature controlled to within -10 to -25 C. This matches the recommended range indicated in the USP as freezer.
Przejdź do
R7632
Retinol
synthetic, ≥95% (HPLC), (Powder or Powder with Lumps)
Retinol
1 of 1 reviewers received a sample product or took part in a promotion
Synonim(y):
Axerophthol, Vitamin A, Vitamin A alcohol, Vitamin A1, all-trans-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraen-1-ol
Zaloguj się, aby wyświetlić ceny organizacyjne i kontraktowe.
Wybierz wielkość
Zmień widok
| Do Państwa/SKU | Dostępność | Cena netto |
|---|---|---|
25 mg | Skontaktuj się z Obsługą Klienta, aby uzyskać informacje na temat dostępności | 372,00 zł |
100 mg | Skontaktuj się z Obsługą Klienta, aby uzyskać informacje na temat dostępności | 574,00 zł |
250 mg | Skontaktuj się z Obsługą Klienta, aby uzyskać informacje na temat dostępności | 1090,00 zł |
500 mg | Skontaktuj się z Obsługą Klienta, aby uzyskać informacje na temat dostępności | 1570,00 zł |
1 g | Skontaktuj się z Obsługą Klienta, aby uzyskać informacje na temat dostępności | 2560,00 zł |
Informacje o tej pozycji
Wzór empiryczny (zapis Hilla):
C20H30O
Numer CAS:
Masa cząsteczkowa:
286.45
NACRES:
NA.79
PubChem Substance ID:
eCl@ss:
34058018
UNSPSC Code:
12352205
EC Number:
200-683-7
MDL number:
Beilstein/REAXYS Number:
403040
372,00 zł
Skontaktuj się z Obsługą Klienta, aby uzyskać informacje na temat dostępności
Pomoc techniczna
Potrzebujesz pomocy? Nasz zespół doświadczonych naukowców chętnie Ci pomoże.
Pozwól nam pomócbiological source
synthetic
Quality Segment
assay
≥95% (HPLC)
form
(Powder or Powder with Lumps)
specific activity
~2700 U/mg
technique(s)
HPLC: suitable
color
yellow to very dark yellow, to Very Dark Orange
mp
61-63 °C (lit.)
shipped in
dry ice
storage temp.
−20°C
SMILES string
CC1(C)C(/C=C/C(C)=C/C=C/C(C)=C/CO)=C(C)CCC1
InChI
1S/C20H30O/c1-16(8-6-9-17(2)13-15-21)11-12-19-18(3)10-7-14-20(19,4)5/h6,8-9,11-13,21H,7,10,14-15H2,1-5H3/b9-6+,12-11+,16-8+,17-13+
InChI key
FPIPGXGPPPQFEQ-OVSJKPMPSA-N
General description
Retinol or vitamin A alcohol is the main circulating form of vitamin A. It is not biologically active. Retinol or all-trans-retinol is a 20-carbon molecule with cyclohexenyl ring, a side chain with four double bonds (in trans configuration), and an alcohol end group.
Application
Retinol has been used:
- for the synthesis of all-trans-retinoic acid in HepG2 cells
- to study the effect of retinol on the growth of murine normal colonic cells cultured as organoids
- as a standard for determination of vitamin A in cells
- as a component of chemically defined medium for testis organ culture and spermatogenesis in vitro.
Biochem/physiol Actions
Retinol and its derivatives exhibit anti-aging properties. In addition, it also acts as an anti-wrinkle agent. However, due to its photoinstability and skin irritation potency, it is not widely used in cosmetic formulations. Retinol is used in the treatment of dermatoses including photoaging. Its deficiency is associated with the development of xerosis and follicular hyperkeratosis.
Retinol works as a precursor of active retinoids. It is converted to retinaldehyde and subsequently to retinoic acid. All-trans and 9-cis-retinoic acid are the ligands for nuclear receptors, retinoic acid receptors (RARs) and retinoid X receptors (RXRs). These receptors are transcriptional regulators of various genes.
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
Light protecting glass vial.
Ta strona może zawierać tekst przetłumaczony maszynowo.
1 of 1
Ta pozycja | |||
|---|---|---|---|
| assay ≥95% (HPLC) | assay ≥95.0% (HPLC) | assay ≥97.5% (HPLC) | assay ≥95% (HPLC) |
| biological source synthetic | biological source synthetic | biological source synthetic | biological source - |
| technique(s) HPLC: suitable | technique(s) - | technique(s) - | technique(s) HPLC: suitable |
| shipped in dry ice | shipped in dry ice | shipped in dry ice | shipped in dry ice |
| form (Powder or Powder with Lumps) | form (Powder or Crystal with Lumps) | form (Powder or Powder with Lumps) | form powder |
| storage temp. −20°C | storage temp. −20°C | storage temp. −20°C | storage temp. −20°C |
Still not finding the right product?
Explore all of our products under Retinol
signalword
Danger
hcodes
Hazard Classifications
Aquatic Chronic 4 - Eye Irrit. 2 - Repr. 1B - Skin Sens. 1
Klasa składowania
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 1
ppe
dust mask type N95 (US), Eyeshields, Gloves
Wybierz jedną z najnowszych wersji:
Masz już ten produkt?
Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.
-
The certificate specifies a storage temperature of -20°C; are there any criteria for temperatures above or below that temperature?
1 answer-
Helpful?
-
-
Is the exact weight of the substance defined in the certificate? If the answer is no, can you determine/guarantee a deviation range of the the item weight?
1 answer-
The overfill tolerance for this product varies depending on the pack size. For 25 mg, the overfill tolerance is +1.0 mg. For 100 mg, the overfill tolerance is +5 mg. For 250 mg, the overfill tolerance is +10 mg. For 500 mg, the overfill tolerance is +25 mg. For 1 g, the overfill tolerance is +0.05 g.
Helpful?
-
-
How can I determine the shelf life / expiration / retest date of this product?
1 answer-
If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdfHelpful?
-
-
How is shipping temperature determined? And how is it related to the product storage temperature?
1 answer-
Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
Helpful?
-