PLA0296

Goat anti-FUS Antibody, Affinity Purified

Powered by Bethyl Laboratories, Inc.

• Synonim(y): 75 kDa DNA-pairing protein, ALS6, ETM4, FUS1, HNRNPP2, POMP75, TLS, amyotrophic lateral sclerosis 6, derived from t(12;16) malignant liposarcoma, fus-like protein, fused in sarcoma, fusion, fusion (involved in t(12;16) in malignant liposarcoma), fusion gene in myxoid liposarcoma, heterogeneous nuclear ribonucleoprotein P2, hnRNP-P2, oncogene FUS, oncogene TLS, translocated in liposarcoma, translocated in liposarcoma protein
• Kod UNSPSC: 12352203
• NACRES: NA.41

Właściwości

• pochodzenie biologiczne: goat
• Poziom jakości: 100
• forma przeciwciała: affinity purified immunoglobulin
• rodzaj przeciwciała: primary antibodies
• klasa czystości: Powered by Bethyl Laboratories, Inc.
• reaktywność gatunkowa: human, mouse
• metody: immunohistochemistry: 1:500-1:2,000; immunoprecipitation (IP): 2- 10 μg/mg; western blot: 1:2,000- 1:10,000
• nr dostępu: P35637
• numer dostępu UniProt: P35637
• Warunki transportu: wet ice
• temp. przechowywania: 2-8°C
• docelowa modyfikacja potranslacyjna: unmodified
• informacje o genach: goat ... FUS(2521)

Opis

Immunogen

The epitope recognized by PLA0296 maps to a region between residue 1 and 50 of human Fusion (involved in t(12;16) in malignant liposarcoma) using the numbering given in entry P35637 (GeneID 2521).

Postać fizyczna

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide

Inne uwagi

FUS has been identified as a frequent translocation fusion partner of various transcription factors. FUS fusion genes have been shown to be associated with multiple tumor types which include liposarcoma, leukemia, histocytoma, and sarcoma. FUS is a multifunctional RNA-binding protein that associates with the nuclear matrix and Cajal bodies and appears to play a role in splicesome assembly, pre-mRNA splicing, DNA repair, transcriptional regulation and homologous recombination.

Oświadczenie o zrzeczeniu się odpowiedzialności

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

This page may contain text that has been machine translated.

Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 12 - Non Combustible Liquids
• Klasa zagrożenia wodnego (WGK): nwg
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable