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Merck

PLA0291

Goat anti-SMC1 Antibody, Affinity Purified

Powered by Bethyl Laboratories, Inc.

Synonim(y):

CDLS2, DXS423E, KIAA0178, SB1.8, SMC protein 1A, SMC-1-alpha, SMC-1A, SMC1, SMC1 (structural maintenance of chromosomes 1; yeast)-like 1, SMC1 structural maintenance of chromosomes 1-like 1 (yeast), SMC1L1, SMC1alpha, Smcb, segregation of mitotic chromosomes 1

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Informacje o tej pozycji

NACRES:
NA.41
UNSPSC Code:
12352203
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biological source

goat

Quality Level

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

species reactivity

human, mouse

technique(s)

immunohistochemistry: 1:500-1:2,000, immunoprecipitation (IP): 2- 10 μg/mg, western blot: 1:2,000- 1:10,000

accession no.

NP_006297.2

shipped in

wet ice

storage temp.

2-8°C

Gene Information

goat ... SMC1(8243)

Immunogen

The epitope recognized by PLA0291 maps to a region between residue 1183 and 1233 of human Structural Maintenance of Chromosomes 1 using the numbering given in entry NP_006297.2 (GeneID 8243).

Physical form

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide

Other Notes

Structural maintenance of chromosomes (SMC) proteins are part of the cohesin and condensin multisubunit complexes that play a critical role in chromosome organization, segregation, gene regulation, and DNA repair. The core cohesin complex includes a heterodimer of SMC1 and SMC3 that functions by forming a ring-like structure that holds sister chromatids together. Cohesin is important to sister chromatid separation and segregation during mitosis and meiosis and also plays a role in double-strand break repair by homologous recombination.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Klasa składowania

12 - Non Combustible Liquids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable



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Eui Young So et al.
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The bone marrow (BM) is one of the organs that is sensitive to acute exposure of ionizing radiation (IR); however, the mechanism of its high sensitivity to IR remains to be elucidated. BM is differentiated into dendritic cells (DC) with