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Informacje o tej pozycji
NACRES:
NA.41
UNSPSC Code:
12352203
Pomoc techniczna
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Pozwól nam pomócbiological source
goat
Quality Level
antibody form
affinity purified immunoglobulin
antibody product type
primary antibodies
species reactivity
human, mouse
technique(s)
immunohistochemistry: 1:500-1:2,000, immunoprecipitation (IP): 2- 10 μg/mg, western blot: 1:2,000- 1:10,000
accession no.
NP_006297.2
shipped in
wet ice
storage temp.
2-8°C
Gene Information
goat ... SMC1(8243)
Immunogen
The epitope recognized by PLA0291 maps to a region between residue 1183 and 1233 of human Structural Maintenance of Chromosomes 1 using the numbering given in entry NP_006297.2 (GeneID 8243).
Physical form
Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
Other Notes
Structural maintenance of chromosomes (SMC) proteins are part of the cohesin and condensin multisubunit complexes that play a critical role in chromosome organization, segregation, gene regulation, and DNA repair. The core cohesin complex includes a heterodimer of SMC1 and SMC3 that functions by forming a ring-like structure that holds sister chromatids together. Cohesin is important to sister chromatid separation and segregation during mitosis and meiosis and also plays a role in double-strand break repair by homologous recombination.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Klasa składowania
12 - Non Combustible Liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
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Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.
Eui Young So et al.
Cancer biology & therapy, 15(7), 906-910 (2014-04-24)
The bone marrow (BM) is one of the organs that is sensitive to acute exposure of ionizing radiation (IR); however, the mechanism of its high sensitivity to IR remains to be elucidated. BM is differentiated into dendritic cells (DC) with