PLA0108

Rabbit anti-DDB1 Antibody, Affinity Purified

Powered by Bethyl Laboratories, Inc.

• Synonim(y): 127kDa, DDB p127 subunit, DDBA, DNA damage-binding protein a, Damage-specific DNA-binding protein 1, HBV X-associated protein 1, UV-DDB 1, UV-DDB1, UV-damaged DNA-binding factor, UV-damaged DNA-binding protein 1, XAP-1, XAP1, XPCE, XPE, XPE-BF, XPE-binding factor, damage-specific DNA binding protein 1, damage-specific DNA binding protein 1 (127kD), xeroderma pigmentosum group E-complementing protein
• Kod UNSPSC: 12352203
• NACRES: NA.41

Właściwości

• pochodzenie biologiczne: rabbit
• Poziom jakości: 100
• forma przeciwciała: affinity purified immunoglobulin
• rodzaj przeciwciała: primary antibodies
• klasa czystości: Powered by Bethyl Laboratories, Inc.
• reaktywność gatunkowa: human, mouse
• stężenie: 0.2 mg/mL
• metody: immunohistochemistry: 1:500- 1:2,000; immunoprecipitation (IP): 2-5 μg/mg; western blot: 1:1,000- 1:10,000
• nr dostępu: Q13289
• numer dostępu UniProt: Q16531
• Warunki transportu: wet ice
• temp. przechowywania: 2-8°C
• docelowa modyfikacja potranslacyjna: unmodified
• informacje o genach: rabbit ... DDB1(1642)

Opis

Immunogen

The epitope recognized by PLA0108 maps to a region between residue 1100 and the C-terminus (residue 1140) of human damage-specific DNA binding protein 1 using the numbering given in TrEMBL entry Q13289 (GeneID 1642).

Postać fizyczna

Tris-buffered Saline containing 0.1% BSA containing 0.09% Sodium Azide

Inne uwagi

DDB1 (DNA Damage Binding Protein 1) is a subunit of the DNA damage-binding protein complex (DDB) involved in DNA repair. As part of a complex with Cul4-based ubiquitin ligase, Cul4-Ddb1 can directly modify chromatin through the ubiquitination of histones as well as ubiquitinate other chromatin bound factors. A deficiency in Cul4-Ddb1 ubiquitin ligase has been associated with xeroderma pigmentosum, a heritable disease characterized by defects in nucleotide excision repair and skin cancer development.

Oświadczenie o zrzeczeniu się odpowiedzialności

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 12 - Non Combustible Liquids
• Klasa zagrożenia wodnego (WGK): WGK 1
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable