P4623

Anti-phospho-Interferon-α Receptor Type I (pSer⁵³⁵/pSer⁵³⁹) Subunit 1 antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

• Synonim(y): Anti-phospho-IFNα Receptor Type I (pSer⁵³⁵/pSer⁵³⁹) Subunit 1, Anti-phospho-IFNARI
• UNSPSC Code: 12352203
• NACRES: NA.46
• MDL number: MFCD07370443
• Conjugate: unconjugated
• Clone: polyclonal
• Application: WB
• Citations: 2

Właściwości

• biological source: rabbit
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• species reactivity: rat, mouse, bovine, human
• technique(s): western blot: 1:1,000 using using FLAG^® immunoprecipitates from HEK 293 cells transfected with Mock, IFNAR1 wild type, or IFNAR1 S535A and S539A mutants
• UniProt accession no.: P17181
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: phosphorylation (pSer535/pSer539)
• Gene Information: human ... IFNAR1(3454) ; mouse ... Ifnar1(15975) ; rat ... Ifnar1(288264)

Opis

Immunogen

synthetic phosphopeptide corresponding to the amino acid residues surrounding the human phospho-interferon-α receptor type I (pSer⁵³⁵/pSer⁵³⁹) subunit 1.

Biochem/physiol Actions

Type I interferons (IFNα, IFNβ and IFNω) are pleotropic cytokines that mediate their cellular activities by binding to specific Type I IFN receptors. The functions of IFNα/ IFNα Receptor Type I axis include antiproliferative, antiviral and immunomodulatory activities.

Physical form

Solution in 10 mM HEPES, pH 7.5, 150 mM NaCl, 100 μg/mL BSA, and 50% glycerol.

Legal Information

FLAG is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Informacja o środkach bezpieczeństwa

• Klasa składowania: 10 - Combustible liquids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)