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P2658

Poly-L-lysine hydrochloride

suitable for cell culture, Mol wt 15,000-30,000

Synonim(y):

L-Lysine hydrochloride homopolymer

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Do Państwa/SKUDostępnośćCena netto
25 mg
Skontaktuj się z Obsługą Klienta, aby uzyskać informacje na temat dostępności
564,00 zł
100 mg
Skontaktuj się z Obsługą Klienta, aby uzyskać informacje na temat dostępności
1720,00 zł
500 mg
Skontaktuj się z Obsługą Klienta, aby uzyskać informacje na temat dostępności
6910,00 zł
1 g
Skontaktuj się z Obsługą Klienta, aby uzyskać informacje na temat dostępności
9590,00 zł

Informacje o tej pozycji

Numer CAS:
26124-78-7
UNSPSC Code:
12352209
eCl@ss:
32160406
NACRES:
NA.26
MDL number:
MFCD00081870

564,00 zł

Skontaktuj się z Obsługą Klienta, aby uzyskać informacje na temat dostępności
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Nazwa produktu

Poly-L-lysine hydrochloride, mol wt 15,000-30,000

form

powder or solid

Quality Segment

200

mol wt

15,000-30,000

technique(s)

cell culture | mammalian: suitable

color

white to light yellow

application(s)

cell analysis

storage temp.

−20°C

Application

Poly-lysine with mol. wt. >70,000 is useful in promoting cell adhesion to solid substrates.
Poly-L-lysine hydrochloride has been used to coat glass slides and coverslips to facilitate cell attachment.

Biochem/physiol Actions

L-Lysine is believed to prevent osteoporosis of bones, which is a characteristics of vascular calcification. Glutaric aciduria type I and pyridoxine-dependent epilepsy occurs due to lack of L-lysine catabolic pathway. Lysine participates in the regulation of NO (nitric oxide) synthesis. It possesses antiviral activity, therefore it is used in the treatment of Herpes simplex. L-Lysine is associated with a number of biochemical reactions such as acetylation, O-linked glycosylation, ubiquitination and protein methylation. Poly-L-lysine is considered as a biocompatible polymer and serves for the purpose of drug delivery across cell membrane. It is useful as one of the nanosized contrast agents in MRI (magnetic resonance imaging).

Analysis Note

Molecular weight based on viscosity.

Other Notes

For additional technical information on polyamino acids please visit the Polyamino acid FAQ resource.
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Ta pozycja
P9404P1524P1024
Poly-L-lysine hydrochloride mol wt 15,000-30,000

Sigma-Aldrich

P2658

Poly-L-lysine hydrochloride

Poly-L-lysine hydrochloride mol wt >30,000

Sigma-Aldrich

P9404

Poly-L-lysine hydrochloride

Poly-L-lysine hydrobromide mol wt ≥300,000

Sigma-Aldrich

P1524

Poly-L-lysine hydrobromide

Poly-D-lysine hydrobromide mol wt ≥300,000

Sigma-Aldrich

P1024

Poly-D-lysine hydrobromide

form

powder or solid

form

powder

form

powder

form

powder or solid

technique(s)

cell culture | mammalian: suitable

technique(s)

FTIR: suitable, cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

300

color

white to light yellow

color

white to light yellow

color

white to off-white

color

white to off-white

application(s)

cell analysis

application(s)

-

application(s)

cell analysis

application(s)

-

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Klasa składowania

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certyfikaty analizy (CoA)

Lot/Batch Number

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Questions

1–4 of 4 Questions  

  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      Helpful?

  2. What's the sterile level of this product? Meanwhile, does γ-irradiation damage your γ-irradiated products.

    1 answer

    1. This particular product is non-sterile as it is not gamma irradiated. Poly-L-lysine products are offered that are gamma-irradiated that are quality guaranteed for sterility and verified to perform as a coating factor for cell attachment. The effects of gamma irradiation on polymers in great detail are discussed in the citation below. Chain scission and chain crosslinking can occur after being gamma irradiated.

      Naikwadi AT, Sharma BK, Bhatt KD, Mahanwar PA. Gamma Radiation Processed Polymeric Materials for High Performance Applications: A Review. Front Chem. 2022 Mar 14;10:837111. doi: 10.3389/fchem.2022.837111. PMID: 35360545; PMCID: PMC8964295.

      Helpful?

  3. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  4. Hello, can you confirm the chemical nature of the termini of this polymer? Is it -NH2 and -COOH? or -NCH3 and -COCH3?

    1 answer

    1. The carboxyl end of this material has a free -COOH and the amino end has a free -NH2.

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