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P0713
Anti-Protein Kinase Cζ antibody produced in rabbit
whole antiserum
Synonim(y):
Anti-PKC ζ
Zaloguj sięWyświetlanie cen organizacyjnych i kontraktowych
About This Item
Numer MDL:
Kod UNSPSC:
12352203
pochodzenie biologiczne
rabbit
białko sprzężone
unconjugated
forma przeciwciała
whole antiserum
rodzaj przeciwciała
primary antibodies
klon
polyclonal
masa cząsteczkowa
antigen 78 kDa
zawiera
15 mM sodium azide
reaktywność gatunkowa
rat, mouse
metody
microarray: suitable
western blot: suitable using rat brain extract and mouse NIH3T3 fibroblast cell lysate
numer dostępu UniProt
Warunki transportu
dry ice
temp. przechowywania
−20°C
informacje o genach
mouse ... Prkcz(18762)
rat ... Prkcz(25522)
Opis ogólny
Protein Kinase C (PKC) is a 76-93 kD phospholipid-dependent enzyme that belongs to serine/threonine protein kinases family. It has a pivotal role in cell growth and differentiation, modulation of neurotransmission, signal transduction and oncogenesis. PKC ζ isoform is expressed mainly in many cells and tissues and is activated by cis- unsaturated fatty acids. Anti-protein kinase C ζ antibody can be used for studying differential tissue expression and intracellular localization of PKC ζ. It can also be used for studying PKC expression in normal and neoplastic tissues. Rabbit anti-protein kinase C ζ antibody reacts specifically with PKC ζ (78 kD) from rat brain extract. The product is also specific for PKC ζ (78-80 kD proteins appearing as doublet) from NIH 3T3 mouse fibroblasts lysate.
Immunogen
Synthetic peptide corresponding to the C-terminal variable (V5) region (amino acids 577-592) of PKC ζ coupled to KLH.
Przechowywanie i stabilność
For continuous use, store at 2-8 °C for up to one month.For extended storage freeze in working aliquots.Repeated freezing and thawing is not recommended.Storage in "frost-free" freezers is not recommended. Ifslight turbidity occurs upon prolonged storage, clarifythe solution by centrifugation before use.
Oświadczenie o zrzeczeniu się odpowiedzialności
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Kod klasy składowania
12 - Non Combustible Liquids
Klasa zagrożenia wodnego (WGK)
WGK 3
Temperatura zapłonu (°F)
Not applicable
Temperatura zapłonu (°C)
Not applicable
Certyfikaty analizy (CoA)
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Y Nishizuka
Science (New York, N.Y.), 258(5082), 607-614 (1992-10-23)
Hydrolysis of inositol phospholipids by phospholipase C is initiated by either receptor stimulation or opening of Ca2+ channels. This was once thought to be the sole mechanism to produce the diacylglycerol that links extracellular signals to intracellular events through activation
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