N2162
NH125
≥98% (HPLC), solid
Synonim(y):
1-Benzyl-3-cetyl-2-methylimidazolium iodide
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Informacje o tej pozycji
Wzór empiryczny (zapis Hilla):
C27H45IN2
Numer CAS:
Masa cząsteczkowa:
524.56
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
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Pozwól nam pomócQuality Level
assay
≥98% (HPLC)
form
solid
color
white to off-white
mp
88.2-94.9 °C
solubility
DMSO: >20 mg/mL
storage temp.
−20°C
SMILES string
[I-].CCCCCCCCCCCCCCCC[n+]1ccn(Cc2ccccc2)c1C
InChI
1S/C27H45N2.HI/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-19-22-28-23-24-29(26(28)2)25-27-20-17-16-18-21-27;/h16-18,20-21,23-24H,3-15,19,22,25H2,1-2H3;1H/q+1;/p-1
InChI key
RVWOHCBHAGBLLT-UHFFFAOYSA-M
Powiązane kategorie
Biochem/physiol Actions
NH125 exhibits anti-proliferation activity against many cancer cells. It also exhibits antibacterial effects by inhibiting bacterial histidine protein kinase.
NH125 is a novel plant histidine kinase inhibitor and selective mammalian eurkaryotic elongation factor-2 kinase (eEF-2K).
Packaging
Packaged under nitrogen.
Analysis Note
IC50 = 60 nM for eEF-2 kinase vs protein kinase C (IC50= 7.5 μM), protein kinase A (IC50= 80 μM), and calmodulin-dependent kinase II IC50 > 100 μM).
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Klasa składowania
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Numer pozycji handlu globalnego
| SKU | NUMER GTIN |
|---|---|
| N2162-25MG | 04061832449036 |
| N2162-5MG | 04061832449043 |
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