Mucins are soluble in water, forming hazy viscous solutions.
M1778
Mucin from porcine stomach
Type III, bound sialic acid 0.5-1.5 %, partially purified powder
Synonim(y):
MUC
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Wybierz wielkość
10 G
762,00 zł
100 G
2540,00 zł
762,00 zł
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Informacje o tej pozycji
Form:
partially purified powder
Biological source:
Porcine stomach
Przejdź do
Pomoc techniczna
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Pozwól nam pomócbiological source
Porcine stomach
Quality Level
type
Type III
form
partially purified powder
composition
bound sialic acid, 0.5-1.5%
technique(s)
microbiological culture: suitable
solubility
NaOH: soluble 20 mg/mL
storage temp.
2-8°C
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Ta pozycja | |||
|---|---|---|---|
| biological source Porcine stomach | biological source Porcine stomach | biological source Porcine | biological source Porcine skin |
| technique(s) microbiological culture: suitable | technique(s) cell culture | mammalian: suitable | technique(s) cell culture | mammalian: suitable | technique(s) cell culture | mammalian: suitable |
| form partially purified powder | form powder | form lyophilized powder | form lyophilized powder |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. room temp |
| solubility NaOH: soluble 20 mg/mL | solubility 1 M NaOH: soluble 20 mg/mL | solubility - | solubility soluble 20 mg/mL, clear, colorless (in warm tissue culture medium) |
| Quality Level 200 | Quality Level 200 | Quality Level 300 | Quality Level 200 |
General description
Application
Mucin from porcine stomach was used in studies on the binding site of the galactose-specific agglutinin PA-IL from Pseudomonas aeruginosa.[3]
Biochem/physiol Actions
Mucus forms the protective cover for all epithelial surfaces. The major structural component of mucus is gel-forming mucins. The mucus layer covering the intestinal epithelium has the MUC2 mucin as its central molecule. MUC2 is produced by goblet cells.[4]
Preparation Note
Prepared according to the method of Glenister, et al., for use in complex growth media for dental plaque bacteria.
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Klasa składowania
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.
Kenny C Mok et al.
mBio, 11(6) (2020-12-10)
The beneficial human gut bacterium Akkermansia muciniphila provides metabolites to other members of the gut microbiota by breaking down host mucin, but most of its other metabolic functions have not been investigated. A. muciniphila strain MucT is known to use
Leyuan Li et al.
Microbiome, 8(1), 33-33 (2020-03-13)
Human-targeted drugs may exert off-target effects or can be repurposed to modulate the gut microbiota. However, our understanding of such effects is limited due to a lack of rapid and scalable assay to comprehensively assess microbiome responses to drugs. Drugs
C A Saceanu et al.
Journal of clinical microbiology, 31(9), 2371-2374 (1993-09-01)
Early identification and isolation of tuberculosis patients is of utmost importance to minimize the risk of further epidemic spread of the disease. The traditional concentrated acid-fast smears are not very reliable tools for the presumptive diagnosis of tuberculosis. Acid-fast bacillus
Francisco J Alvarez et al.
Applied and environmental microbiology, 81(8), 2770-2780 (2015-02-11)
The pathogenic fungus Candida albicans is the leading cause of vulvovaginal candidiasis (VVC). VVC represents a major quality-of-life issue for women during their reproductive years, a stage of life where the vaginal epithelium is subject to periodic hormonally induced changes
Helen Rose et al.
The Journal of antimicrobial chemotherapy, 63(3), 502-510 (2009-01-21)
The Burkholderia cepacia complex (Bcc) species are important opportunistic pathogens with intrinsic antibiotic resistance. They are also well known as contaminants of disinfectants, yet their biocide susceptibility has not been studied in detail. We investigated Bcc biocide susceptibility and correlated
Produkty
Understand sialic acid structure, function, signaling, and modifications. Easily find products for sialic acid research.
Powiązane treści
Numer pozycji handlu globalnego
| SKU | NUMER GTIN |
|---|---|
| M1778-100G | 04061834041108 |
| M1778-10G | 04061835557660 |
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Can I reconstitute the mucin so that it forms a saliva/snot-like substance? I can't seem to find any papers that have done this...
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What is the Department of Transportation shipping information for this product?
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Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
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What is the molecular weight of Product M1778, Mucin from porcine stomach?
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This product is partially purified from crude mucin, M2378. Sigma has not determined the molecular weight of this product. Neither has the sugar and amino acid composition been determined.
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Is Product M1778, Mucin from porcine stomach, a purified preparation of mucin?
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This product is a partially purified preparation of mucin based on the method of Glenister cited on the product's webpage.
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How can I solubilize Product M1778, Mucin from porcine stomach?
1 answer-
Mucin is not readily soluble in aqueous solutions. Turbid "solutions" will form at about 5 mg/mL in 0.1 M acetate buffer, pH 5.0. To try to increase the solubility, one might try further dilution and sonication, but we have not tried this in our labs.
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What does the "Type" designation in Mucin from porcine stomach mean?
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The type designation does not have any particular biological significance. It is used to emphasize differences in the listings of this product.
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What are the differences between Mucin from porcine stomach Products M2378 and M1778?
1 answer-
Product No. M2378 is a crude mucin preparation. Product No. M1778 is a partially purified powder prepared according to the method described in Glenister, D.A. and Salmon. K. Microbial Ecol. in Health & Disease 1, 31, (1988). The amount of bound sialic acids are also different. Please refer to the specification sheets on our website.
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