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I3525

Interleukin-17A human

≥98% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture

Synonim(y):

CTLA-8, IL-17

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Do Państwa/SKUDostępnośćCena netto
50 μg
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3210,00 zł

Informacje o tej pozycji

UNSPSC Code:
12352202
NACRES:
NA.32
MDL number:

3210,00 zł


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biological source

human

Quality Segment

recombinant

expressed in E. coli

assay

≥98% (SDS-PAGE)

form

lyophilized powder

potency

≤2.0 ng/mL ED50

mol wt

31 kDa

packaging

pkg of 50 μg

technique(s)

cell culture | mammalian: suitable

impurities

endotoxin, tested (endotoxin level is less than 0.1 ng per μg cytokine (1 EU/μg).)

UniProt accession no.

storage temp.

−20°C

Gene Information

human ... IL17A(3605)

Biochem/physiol Actions

IL-17, initially known as CTLA-8, is a T cell-expressed polypeptide that appears to be involved in the regulation of the hematopoietic system. IL-17 has been shown to induce IL-6, IL-8, and G-CSF production by fibroblasts; all of these cytokines have demonstrated effects on hematopoiesis.
Initially known as CTLA-8; is a T cell-expressed polypeptide that appears to be involved in the regulation of the hematopoietic system; has been shown to induce IL-6, IL-8, and G-CSF production by fibroblasts; all of these cytokines have demonstrated effects on hematopoiesis.

Physical form

Lyophilized with no additives.

Analysis Note

  • The biological activity of human IL-17 is measured by its ability to induce IL-6 production using NHDF cells.
  • Biological activity is also determined by the dose-dependent induction of IL-6 in primary human foreskin fibroblast. The expected ED50 is < 2.0 ng/ml, corresponding to a specific activity of > 5 x 105 units/mg.
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I4026SRP3080I5896
technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

assay

≥98% (SDS-PAGE)

assay

≥97% (SDS-PAGE)

assay

≥98% (HPLC), ≥98% (SDS-PAGE)

assay

≥98% (SDS-PAGE)

biological source

human

biological source

mouse

biological source

human

biological source

human

recombinant

expressed in E. coli

recombinant

expressed in E. coli

recombinant

expressed in E. coli

recombinant

expressed in E. coli

Quality Level

100

Quality Level

200

Quality Level

-

Quality Level

200

form

lyophilized powder

form

lyophilized powder

form

lyophilized

form

lyophilized powder


Klasa składowania

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Certyfikaty analizy (CoA)

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Questions

1–2 of 2 Questions  
  1. What is the solution from which product I3525, Interleukin-17A human recombinant, was prepared?

    1 answer
    1. Product I3525, Recombinant Human IL-17A, was lyophilized with no additives, which means it was lyophilized from water and may contain trace amounts of 0.1% TFA (pH 2.0) from being HPLC-purified.

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  2. What is the Department of Transportation shipping information for this product?

    1 answer
    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

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