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Key Documents
H1254
8-Hydroxyquinoline glucuronide
≥95%, powder
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About This Item
Wzór empiryczny (zapis Hilla):
C15H15NO7
Numer CAS:
Masa cząsteczkowa:
321.28
Numer WE:
Numer MDL:
Kod UNSPSC:
12352204
Identyfikator substancji w PubChem:
Próba
≥95%
Postać
powder
kolor
light green
ciąg SMILES
O[C@@H]1[C@H](O[C@H]([C@H](O)[C@H]1O)C(O)=O)Oc2cccc3cccnc23
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Substraty
Substrate for the histochemical demonstration of β-glucuronidase and for quantitative assay systems.
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Kod klasy składowania
11 - Combustible Solids
Klasa zagrożenia wodnego (WGK)
WGK 3
Temperatura zapłonu (°F)
Not applicable
Temperatura zapłonu (°C)
Not applicable
Certyfikaty analizy (CoA)
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Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.
Andrew D Pris et al.
Analytical chemistry, 81(24), 9948-9954 (2009-11-18)
Enabling trace chemical detection equipment utilized in the field to transduce a biodetection assay would be advantageous from a logistics, training, and maintenance standpoint. Described herein is an assay design that uses an unmodified, commercial off-the-shelf (COTS) ion trap mobility
Peter Tobin et al.
British journal of clinical pharmacology, 62(1), 122-129 (2006-07-18)
Irinotecan (CPT-11) is a prodrug that is used to treat metastatic colorectal cancer. It is activated to the topoisomerase poison SN-38 by carboxylesterases. SN-38 is metabolized to its inactive glucuronide, SN-38 glucuronide. The aim of this study was to determine
T P Monson et al.
International journal of radiation oncology, biology, physics, 20(6), 1263-1271 (1991-06-01)
RIF-1 mouse tumors express high levels of beta-glucuronidase activity relative to most normal tissues. The high activity can be exploited for targeting specific drugs preferentially to tumor tissues. In this study we examined the kinetics of 8-hydroxyquinoline (8-OHQ) accumulation in
Direct radioiodination of metabolic 8-hydroxy-quinolyl-glucuronide, as a potential anti-cancer drug.
T Unak et al.
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 47(7), 645-647 (1996-07-01)
8-Hydroxy-quinolyl-glucuronide (8-HOQ-Glu) can be deglucuronidated by the beta-glucoronidase enzyme, which has an activity that is considerably high in certain kinds of cancer cell. Owing to this enzyme activity, 8-HOQ-Glu can be considered as a potential anti-cancer drug. The combination of
Reyhan Yeşilağaç et al.
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 69(2), 299-307 (2010-11-27)
8-Hydroxyquinoline (8-OHQ) is a long-known molecule which due to its metal-complexation ability is frequently used for analysis. It is also called oxine. Oxine and derivatives have been investigated to process antitumor and antimicrobial activities. 8-Hydroxyquinolyl-glucuronide (8-OHQ-Glu) was enzymatically synthesized using
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