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Merck

GW21071

Sigma-Aldrich

Anti-PI3K antibody produced in chicken

affinity isolated antibody, buffered aqueous solution

Synonim(y):

Anti-Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit β isoform

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About This Item

Kod UNSPSC:
12352203
NACRES:
NA.41

pochodzenie biologiczne

chicken

białko sprzężone

unconjugated

forma przeciwciała

affinity isolated antibody

rodzaj przeciwciała

primary antibodies

klon

polyclonal

Formularz

buffered aqueous solution

reaktywność gatunkowa

rat, mouse, human

metody

western blot: suitable

numer dostępu NCBI

numer dostępu UniProt

Warunki transportu

wet ice

temp. przechowywania

−20°C

informacje o genach

human ... PIK3CB(5291)

Immunogen

Immunogen Sequence: GI # 5453894, sequence 58-134
Recombinant phosphoinositide-3-kinase, catalytic, β polypeptide

Zastosowanie

Anti-PI3K antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

Działania biochem./fizjol.

Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit β isoform is an enzyme encoded by the PIK3CB gene in humans. It has been implicated as a participant in signaling pathways regulating cell growth by virtue of its activation in response to various mitogenic stimuli. PI 3-kinase exhibits different isoforms and has a define family of genes encoding distinct PI 3-kinase catalytic subunits that can associate with p85. It is commonly activated in tumors. PI3K pathway is activated in tumors and most commonly through p110α mutation or PTEN deletion.

Postać fizyczna

Solution in phosphate buffered saline containing 0.02% sodium azide.

Oświadczenie o zrzeczeniu się odpowiedzialności

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Kod klasy składowania

12 - Non Combustible Liquids

Klasa zagrożenia wodnego (WGK)

WGK 1

Temperatura zapłonu (°F)

Not applicable

Temperatura zapłonu (°C)

Not applicable

Środki ochrony indywidualnej

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


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Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.

Odwiedź Bibliotekę dokumentów

Lan Liu et al.
Oncology letters, 14(3), 3741-3747 (2017-09-21)
Catalpol is an effective active ingredient that functions as a diuretic and laxative, and exhibits blood sugar-lowering, liver protective, anti-aging and anticancer effects. In traditional Chinese medicine, catalpol is believed to be Yin nourishing. The anticancer effect of catalpol on
Hashem A Dbouk et al.
PloS one, 8(5), e63833-e63833 (2013-06-05)
The PI3-kinase pathway is commonly activated in tumors, most often by loss of PTEN lipid phosphatase activity or the amplification or mutation of p110α. Oncogenic mutants have commonly been found in p110α, but rarely in any of the other catalytic
P Hu et al.
Molecular and cellular biology, 13(12), 7677-7688 (1993-12-01)
Phosphatidylinositol 3-kinase (PI 3-kinase) has been implicated as a participant in signaling pathways regulating cell growth by virtue of its activation in response to various mitogenic stimuli. Here we describe the cloning of a novel and ubiquitously expressed human PI
Dongjin Lv et al.
Molecular medicine reports, 23(3) (2021-01-27)
Long non‑coding RNAs (lncRNAs) are involved in the occurrence and progression of numerous types of cancer. The aim of the present study was to evaluate the effect of the lncRNA maternally expressed gene 3 (MEG3) on the migration and invasion of
Xueliang Qin et al.
3 Biotech, 10(4), 187-187 (2020-04-08)
This study explored the effect of methyl-indole on pancreatic cancer cell viability and investigated the mechanism involved. The viability of pancreatic cells showed a significant suppression on treatment with methyl-indole in dose-based manner. Treatment with 5 µM methyl-indole suppressed Capan-1 cell

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