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D108
1,3-Dipropyl-7-methylxanthine
solid
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Informacje o tej pozycji
Wzór empiryczny (zapis Hilla):
C12H18N4O2
Numer CAS:
Masa cząsteczkowa:
250.30
UNSPSC Code:
41106305
PubChem Substance ID:
MDL number:
Form:
solid
form
solid
color
white
solubility
0.1 M NaOH: soluble, DMSO: soluble
εmax
9,500 at 273 nm
SMILES string
CCCN1C(=O)N(CCC)c2ncn(C)c2C1=O
InChI
1S/C12H18N4O2/c1-4-6-15-10-9(14(3)8-13-10)11(17)16(7-5-2)12(15)18/h8H,4-7H2,1-3H3
InChI key
QVAYTZAGDQIWMB-UHFFFAOYSA-N
Gene Information
human ... ADORA2A(135), ADORA2B(136)
rat ... Adora1(29290), Adora2a(25369)
Biochem/physiol Actions
Caffeine analog with some selectivity for A2 adenosine receptors.
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Klasa składowania
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Powiązane treści
Y S Lau et al.
Journal of neurochemistry, 60(2), 768-771 (1993-02-01)
The effects of the adenosine A1 agonist N6-cyclohexyladenosine (CHA) on MPTP-induced dopamine (DA) depletion in the striatum of C57BL/6 mice were studied. Twenty hours after a single injection of MPTP (30 mg/kg, s.c.), the toxin caused 62% depletion of striatal
J M Gidday et al.
Pediatric research, 33(6), 620-627 (1993-06-01)
The reactivity of retinal arterioles and venules to exogenous and endogenous adenosine was investigated in the newborn piglet eye in vivo. The retinal microcirculation of isoflurane-anesthetized newborn pigs was observed at 310x using videomicroscopy, and changes in the diameter of
M P Rathbone et al.
In vitro cellular & developmental biology : journal of the Tissue Culture Association, 28A(7-8), 529-536 (1992-07-01)
Presumptive astrocytes isolated from 10-day white Leghorn chick embryos, Factor VIII-positive human brain capillary endothelial cells, meningeal fibroblasts from 10-day chick embryos, Swiss mouse 3T3 cells, and human astrocytoma cell lines, SKMG-1 and U373, were rendered quiescent when placed in