C9749

CBiPES hydrochloride

≥98% (HPLC)

• Synonim(y): N-(4′-cyano[1,1′-biphenyl]-3-yl)-N-(3-pyridinylmethyl)-ethanesulfonamide hydrochloride
• Wzór empiryczny (zapis Hilla): C₂₁H₁₉N₃O₂S · HCl
• Numer CAS: 856702-40-4
• Masa cząsteczkowa: 413.92
• Kod UNSPSC: 12352200
• NACRES: NA.77

Właściwości

• Próba: ≥98% (HPLC)
• Postać: powder
• warunki przechowywania: desiccated
• kolor: off-white to light brown
• rozpuszczalność: DMSO: >20 mg/mL
• inicjator: Eli Lilly
• temp. przechowywania: 2-8°C
• InChI: 1S/C21H19N3O2S.ClH/c1-2-27(25,26)24(16-18-5-4-12-23-15-18)21-7-3-6-20(13-21)19-10-8-17(14-22)9-11-19;/h3-13,15H,2,16H2,1H3;1H
• Klucz InChI: QKUHSVQWWZBAKM-UHFFFAOYSA-N

Opis

Działania biochem./fizjol.

CBiPES is a positive allosteric modulator of the mGlu2 receptor. CBiPES attenuates stress-induced hyperthermia and blocks the hyperlocomotor effects of PCP in murine models. In rat brain, CBiPES attenuates ketamine-induced increase in extracellular histamine concentration. This compound is a sulfonamide, different chemical class from other mGlu2R agonists in the Sigma catalog.

Cechy i korzyści

This compound is featured on the Glutamate Receptors (G Protein Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by Eli Lilly. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 11 - Combustible Solids
• Klasa zagrożenia wodnego (WGK): WGK 3
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable