C6491

Chrysomycin B

≥98% (HPLC), solid

• Wzór empiryczny (zapis Hilla): C₂₇H₂₈O₉
• Numer CAS: 83852-56-6
• Masa cząsteczkowa: 496.51
• NACRES: NA.77
• PubChem Substance ID: 24892870
• UNSPSC Code: 12352200
• MDL number: MFCD07370132

Właściwości

• assay: ≥98% (HPLC)
• form: solid
• solubility: DMF: soluble, DMSO: soluble, ethanol: moderately soluble, methanol: moderately soluble
• antibiotic activity spectrum: neoplastics
• mode of action: enzyme | inhibits
• storage temp.: 2-8°C
• SMILES string: COc1cc(C)cc2C(=O)Oc3c(cc(OC)c4c(O)ccc([C@@H]5O[C@H](C)[C@H](O)[C@@](C)(O)[C@H]5O)c34)-c12
• InChI: 1S/C27H28O9/c1-11-8-15-19(17(9-11)33-4)14-10-18(34-5)21-16(28)7-6-13(20(21)22(14)36-26(15)31)23-25(30)27(3,32)24(29)12(2)35-23/h6-10,12,23-25,28-30,32H,1-5H3/t12-,23+,24+,25+,27-/m1/s1
• InChI key: BJPYMDSMDBCKEP-QSMCFSHASA-N

Opis

Biochem/physiol Actions

Antibiotic from Streptomyces sp. Inhibits the catalytic activity of human topoisomerase II.

Antibiotic from Streptomyces sp. Inhibits the catalytic activity of human topoisomerase II. Exhibits antitumor activity against human cell lines K562, HT29, MCF7, PC6, and MKN28.

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Informacja o środkach bezpieczeństwa

• Klasa składowania: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)