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Merck

C4767

β-Cyclodextrin

≥97%

Synonim(y):

beta-Cyclodextrin, Caraway, Cycloheptaamylose, Cyclomaltoheptaose, Schardinger β-Dextrin

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Wybierz wielkość

25 G

618,00 zł

100 G

932,00 zł

500 G

4060,00 zł

618,00 zł


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Informacje o tej pozycji

Wzór empiryczny (zapis Hilla):
C42H70O35
Numer CAS:
Masa cząsteczkowa:
1134.98
UNSPSC Code:
12352302
NACRES:
NA.22
PubChem Substance ID:
EC Number:
231-493-2
Beilstein/REAXYS Number:
78623
MDL number:

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InChI

1S/C42H70O35/c43-1-8-29-15(50)22(57)36(64-8)72-30-9(2-44)66-38(24(59)17(30)52)74-32-11(4-46)68-40(26(61)19(32)54)76-34-13(6-48)70-42(28(63)21(34)56)77-35-14(7-49)69-41(27(62)20(35)55)75-33-12(5-47)67-39(25(60)18(33)53)73-31-10(3-45)65-37(71-29)23(58)16(31)51/h8-63H,1-7H2/t8-,9-,10-,11-,12-,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23-,24-,25-,26-,27-,28-,29-,30-,31-,32-,33-,34-,35-,36-,37-,38-,39-,40-,41-,42-/m1/s1

InChI key

WHGYBXFWUBPSRW-FOUAGVGXSA-N

SMILES string

OC[C@H]1O[C@@H]2O[C@H]3[C@H](O)[C@@H](O)[C@H](O[C@@H]3CO)O[C@H]4[C@H](O)[C@@H](O)[C@H](O[C@@H]4CO)O[C@H]5[C@H](O)[C@@H](O)[C@H](O[C@@H]5CO)O[C@H]6[C@H](O)[C@@H](O)[C@H](O[C@@H]6CO)O[C@H]7[C@H](O)[C@@H](O)[C@H](O[C@@H]7CO)O[C@H]8[C@H](O)[C@@H](O)[C@H](O[C@@H]8CO)O[C@H]1[C@H](O)[C@H]2O

assay

≥97%

form

powder

optical activity

[α]20/D +162±3°, c = 1.5% in H2O

mp

290-300 °C (dec.) (lit.)

solubility

1 M NH4OH: 50 mg/mL

Quality Level

biological source

plant

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Pokaż różnice

1 of 4

Ta pozycja
239760779105B0950000
Betadex European Pharmacopoeia (EP) Reference Standard

B0950000

Betadex

assay

≥97%

assay

≥98% (HPLC)

assay

≥95.0% (HPLC)

assay

-

biological source

microbial

biological source

-

biological source

-

biological source

-

solubility

1 M NH4OH: 50 mg/mL

solubility

water: 10 mg/mL

solubility

-

solubility

-

Quality Level

200

Quality Level

100

Quality Level

100

Quality Level

-

form

powder

form

solid

form

powder

form

-

mp

290-300 °C (dec.) (lit.)

mp

-

mp

290-300 °C (dec.) (lit.)

mp

290-300 °C (dec.) (lit.)

General description

β-Cyclodextrin is a cyclic oligosaccharide consisting of seven glucose subunits joined by α-(1,4) glycosidic bonds forming a truncated conical structure. It is widely used in food, pharmaceutical, cosmetics, and chemicals industries.[1][2]

Application

β-Cyclodextrin is used as a complexing agent in drug delivery because it forms an inclusion complex with a drug molecule. The complex of cyclodextrin increases the aqueous solubility, dissolution rate and bioavailability of poorly water-soluble drugs, which is useful for the delivery of the medical agent to a biological system.[1][3][4][5]
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Klasa składowania

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Masz już ten produkt?

Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.

Odwiedź Bibliotekę dokumentów

Study to explore the mechanism to form inclusion complexes of beta-cyclodextrin with vitamin molecules
Saha S, et al.
Scientific Reports, 6, 35764-35764 (2016)
Preparation and characterization of microparticles of ?-cyclodextrin/glutathione and chitosan/glutathione obtained by spray-drying
Webber V, et al.
Food Research International, 105, 432-439 (2018)
Cyclodextrins
Kurkov SV and Loftsson T
The International journal of pharmacy practice, 453, 167-180 (2013)
Inclusion complexation of tolbutamide with ?-cyclodextrin and hydroxypropyl-?-cyclodextrin
Veiga F, et al.
Journal of psychosomatic obstetrics and gynaecology, 129, 63-71 (1996)
Use of dehydrated beta-cyclodextrin as pharmaceutical excipient
Martini A, et al.
Drug Development and Industrial Pharmacy, 20, 2381-2393 (1994)

Produkty

Techniques for solubilizing metabolically important compounds in aqueous solutions are reviewed.

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Product Information Sheet

Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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