C3595

Anti-Connexin-32 (106-124) antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

• Synonim(y): Anti-CMTX, Anti-CMTX1, Anti-CX32
• Numer MDL: MFCD01633266
• Kod UNSPSC: 12352203
• NACRES: NA.41

Właściwości

• pochodzenie biologiczne: rabbit
• białko sprzężone: unconjugated
• forma przeciwciała: affinity isolated antibody
• rodzaj przeciwciała: primary antibodies
• klon: polyclonal
• Postać: buffered aqueous solution
• masa cząsteczkowa: antigen 27 kDa
• reaktywność gatunkowa: mouse, human, rat
• metody: immunohistochemistry (frozen sections): 1:400 using frozen rat liver sections; western blot: 1:400 using a rat liver membrane preparation
• numer dostępu UniProt: P08034
• Warunki transportu: dry ice
• temp. przechowywania: −20°C
• docelowa modyfikacja potranslacyjna: unmodified
• informacje o genach: human ... GJB1(2705) ; mouse ... Gjb1(14618) ; rat ... Gjb1(29584)

Opis

Opis ogólny

Connexins (Cx) are a multi-gene family of highly related proteins with molecular weights ranging from 26 to 70 kDa. The structure of connexin molecules includes a cytoplasmic N-terminal region, four transmembrane domains, two extracellular loops, and a C-terminal cytoplasmic tail of varying length. The 27kD connexin protein (connexin 32, Cx32) is expressed in several tissues.

Immunogen

synthetic human connexin-32 peptide (amino acids 106-124).

Zastosowanie

Anti-Connexin 32 (265-279) antibody produced in rabbit is suitable for immunohistochemistry (frozen sections) at a dilution of 1:400 using frozen rat liver tissue. It is also suitable for western blot at a dilution of 1:400 using a rat liver membrane preparation.

Anti-Connexin-32 (106-124) antibody produced in rabbit has been used in:

• western blotting
• immunofluorescence
• immunohistology

Działania biochem./fizjol.

Cx32 mutations is associated with X-linked Charcot-Marie-Tooth (CMTX) disease, which leads to myelin disruption and axonal degeneration.

Postać fizyczna

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin with 15 mM sodium azide.

Oświadczenie o zrzeczeniu się odpowiedzialności

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 10 - Combustible liquids
• Klasa zagrożenia wodnego (WGK): nwg
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable