C3242

CDKi hydrochloride

≥98% (HPLC), solid

• Synonim(y): 2,4-Diamino-5-oxo-pyrimidine hydrochloride
• Wzór empiryczny (zapis Hilla): C₄H₆N₄O · xHCl
• Numer CAS: 70035-83-5
• Masa cząsteczkowa: 126.12 (free base basis)
• UNSPSC Code: 12352200
• PubChem Substance ID: 24724437
• MDL number: MFCD08277042

Właściwości

• assay: ≥98% (HPLC)
• form: solid
• solubility: H₂O: 21 mg/mL
• storage temp.: 2-8°C
• SMILES string: Cl[H].Nc1ncc(O)c(N)n1
• InChI: 1S/C4H6N4O.ClH/c5-3-2(9)1-7-4(6)8-3;/h1,9H,(H4,5,6,7,8);1H
• InChI key: KEFSYBXFZWLDQU-UHFFFAOYSA-N

Opis

Biochem/physiol Actions

CDKi hydrochloride is a potent and selective ATP competitiive inhibitor of cycB-CDK1, cycE-CDK2, and cycD1-CDK4. Demonstrates significant inhibitory activity against a variety of tumor type both in vitro and in vivo.

Features and Benefits

This compound is featured on the CDKs page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

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Informacja o środkach bezpieczeństwa

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Klasa składowania: 13 - Non Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves