B5416

8-Bromo-cyclic adenosine diphosphate ribose

85% (HPLC), lyophilized powder

• Synonim(y): Br-cADP-ribose, Br-cADPR
• Wzór empiryczny (zapis Hilla): C₁₅H₂₀BrN₅O₁₃P₂
• Numer CAS: 151898-26-9
• Masa cząsteczkowa: 620.20
• UNSPSC Code: 41106305
• eCl@ss: 32160414
• PubChem Substance ID: 329773258
• NACRES: NA.51
• MDL number: MFCD00274402
• Assay: 85% (HPLC)
• Form: lyophilized powder
• Solubility: H₂O: 5 mg/mL
• Storage temp.: −20°C

Właściwości

• Quality Segment: 200
• assay: 85% (HPLC)
• form: lyophilized powder
• color: white
• solubility: H₂O: 5 mg/mL
• storage temp.: −20°C
• SMILES string: Nc1ncnc2n([C@@H]3O[C@@H]4COP(O)(=O)OP(=O)(O[C@@H]5O[C@H](CO)[C@@H](O)[C@H]5O)O[C@H]4[C@H]3O)c(Br)nc12
• InChI: 1S/C15H20BrN5O13P2/c16-15-20-6-11(17)18-3-19-12(6)21(15)13-9(25)10-5(30-13)2-29-35(26,27)34-36(28,32-10)33-14-8(24)7(23)4(1-22)31-14/h3-5,7-10,13-14,22-25H,1-2H2,(H,26,27)(H2,17,18,19)/t4-,5-,7-,8-,9-,10-,13-,14+,36?/m1/s1
• InChI key: PLQQKRPSINJWTK-VNMBDIRDSA-N

Opis

Biochem/physiol Actions

An antagonist of cyclic ADP-ribose (cADPR), and an endogenous metabolite of β-NAD⁺. cADPR has been shown to regulate calcium release from the endoplasmic and sarcoplasmic reticulum. In cells, cADPR is synthesized by ADP-ribosyl cyclase or CD38, a lymphocyte differentiation antigen.

Physical form

Lyophilized powder containing 10-20% sodium phosphate buffer salts

Preparation Note

Prepared enzymatically

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Informacja o środkach bezpieczeństwa

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Klasa składowania: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves