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A5222

D-Amino Acid Oxidase from porcine kidney

powder, ≥1.5 units/mg solid

Synonim(y):

D-AAO, D-Amino acid: oxygen oxidoreductase (deaminating)

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Do Państwa/SKUDostępnośćCena netto
200 units
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1860,00 zł

Informacje o tej pozycji

Numer CAS:
UNSPSC Code:
12352204
NACRES:
NA.54
EC Number:
232-563-5
MDL number:
Numer WE:
Specific activity:
≥1.5 units/mg solid

1860,00 zł


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form

powder

Quality Segment

specific activity

≥1.5 units/mg solid

storage temp.

−20°C

Application

D-amino acid oxidase (DAO) is a potential target molecule for the treatment of chronic pain and schizophrenia [1][2]. D-amino acid oxidase is used to oxidize D-amino acids to their corresponding imino acids.

Other Notes

One unit will oxidatively deaminate 1.0 μmole of D-alanine to pyruvate per minute at pH 8.3 at 25 °C, in the presence of a catalase.
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Ta pozycja
D7876A9378L5135
specific activity

≥1.5 units/mg solid

specific activity

≥0.05 unit/mg solid

specific activity

≥4.0 units/mg protein

specific activity

≥60 units/mg protein

form

powder

form

solid

form

aqueous suspension

form

lyophilized powder

storage temp.

−20°C

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

−20°C

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200


Klasa składowania

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)



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Certyfikaty analizy (CoA)

Lot/Batch Number

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Questions

1–3 of 3 Questions  
  1. What is the shelf life of this product at -20 °C?

    1 answer
    1. This product is not assigned an expiration or retest date. Products that are robust in nature and extremely stable, in the original unopened container, are not assigned an expiration date or retest schedule. These products will have no dating reported on either the label or the Certificate of Analysis. Products that are not assigned an expiration or retest date are covered by a warranty period of 1 year from the date of product shipment.
      Full Product Dating Information may be reviewed at the link below:
      https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/190/408/product-dating-information-ms.pdf

      Helpful?

  2. If I store it at -4 degrees Celsius instead of -20 degrees Celsius, will the enzyme denature so much that it cannot be used? Also, if I expose it to room temperature for use in an experiment and then store it at -4 degrees Celsius, will it be usable again

    1 answer
    1. This product should be stored at -20 °C as a powder. Information on storing the product in solution is not available, and it is recommended to prepare the product fresh before use.

      Helpful?

  3. Hello, I am doing my research about D-amino acid oxidase from porcine kidney. For further calculations I need molar extinction coefficient of pkDAAO. Maybe You have bigger description or some kind of information about it? Thank You.

    1 answer
    1. There are two extinction coefficient values available:

      Assuming all Cys residues form cystines - 1.935 at 280 nm in water, 0.1% (1 g/L)
      Assuming all Cys residues are reduced - 1.929 at 280 nm in water, 0.1% (1 g/L)

      Please see the link below to review this and additional information available at Expasy:
      https://web.expasy.org/cgi-bin/protparam/protparam1?P00371@noft@

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