A3097

[Pro¹⁸, Asp²¹]-Amyloid β Protein Fragment 17-21 trifluoroacetate salt

≥98% (HPLC), solid

• Wzór empiryczny (zapis Hilla): C₃₃H₄₃N₅O₈
• Numer CAS: 182912-74-9
• Masa cząsteczkowa: 637.72
• UNSPSC Code: 12352200
• MDL number: MFCD01862668

Właściwości

• assay: ≥98% (HPLC)
• form: solid
• UniProt accession no.: P05067
• storage temp.: −20°C
• SMILES string: CC(C)C[C@H](N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](Cc3ccccc3)C(=O)N[C@@H](CC(O)=O)C(O)=O
• Gene Information: human ... APP(351)

Opis

Biochem/physiol Actions

Inhibits amyloid formation in vitro and amyloid neurotoxicity in cell culture, reduces in vivo cerebral amyloid deposition and blocks amyloid fibrial formation in rat brain.

Inhibits amyloid formation in vitro, prevents amyloid neurotoxicity in cell culture, reduces in vivo cerebral amyloid deposition and completely blocks amyloid fibrial formation in rat brain.

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