06627
2-Aminoacridone
BioReagent, suitable for fluorescence, ≥98.0% (HPLC)
Synonim(y):
2-Amino-9(10H)-acridinone, 2-amino-10H-acridin-9-one, AMAC
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Wybierz wielkość
25 MG
564,00 zł
100 MG
1350,00 zł
564,00 zł
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Informacje o tej pozycji
Wzór empiryczny (zapis Hilla):
C13H10N2O
Numer CAS:
Masa cząsteczkowa:
210.23
NACRES:
NA.32
PubChem Substance ID:
UNSPSC Code:
12352108
MDL number:
Beilstein/REAXYS Number:
172520
Przejdź do
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Pozwól nam pomócproduct line
BioReagent
Quality Level
assay
≥98.0% (HPLC)
form
powder
mol wt
210.23 g/mol
concentration
≤100%
color
yellow to dark yellow
solubility
DMF: soluble, DMSO: soluble
fluorescence
λex 420 nm; λem 542 nm in 0.1 M Tris pH 8.0
suitability
suitable for fluorescence
InChI
1S/C13H10N2O/c14-8-5-6-12-10(7-8)13(16)9-3-1-2-4-11(9)15-12/h1-7H,14H2,(H,15,16)
InChI key
PIGCSKVALLVWKU-UHFFFAOYSA-N
Powiązane kategorie
1 of 4
Ta pozycja | |||
|---|---|---|---|
| suitability suitable for fluorescence | suitability - | suitability - | suitability - |
| fluorescence λex 420 nm; λem 542 nm in 0.1 M Tris pH 8.0 | fluorescence - | fluorescence - | fluorescence - |
| solubility DMF: soluble, DMSO: soluble | solubility - | solubility - | solubility - |
| Quality Level 100 | Quality Level 100 | Quality Level 100 | Quality Level 100 |
| assay ≥98.0% (HPLC) | assay ≥99.0% (T) | assay 97% | assay 97% |
| product line BioReagent | product line - | product line - | product line - |
Application
2-Aminoacridone is a highly fluorescent aromatic, which contains a primary amine group that reacts with an aldehyde group at the reducing end of a carbohydrate and is reduced to a stable amine derivative by sodium borohydride (NaBH4). Picomolar levels of glycan compounds can be detected using this fluorophore. The resulting derivatzed compounds can be separated by reverse-phase HPLC and detected by positive-ion electrospray MS . An intense fluorescent, hydrophobic probe that is stable over a wide pH range is useful in the derivatization of glycans to allow for the analysis of complex oligosaccharides using micellar electrokinetic capillary chromatography and reverse- and normal-phase chromatography coupled with mass spectroscopy to determine relative concentrations and structural identity of individual oligosaccharides . The λ excitation and λ emission are 425 nm and 532 nm, respectively.
Fluorescent label for glycans and saccharides.
Fluorescent label for glycans and saccharides. The analysis of fluorophore-labeled glycans by high-resolution polyacrylamide gel electrophoresis.
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
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signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Klasa składowania
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.
Yuqing Chang et al.
Analytical biochemistry, 427(1), 91-98 (2012-05-23)
A quantitative and highly sensitive method for the analysis of glycosaminoglycan (GAG)-derived disaccharides that relies on capillary electrophoresis (CE) with laser-induced fluorescence detection is presented. This method enables complete separation of 17 GAG-derived disaccharides in a single run. Unsaturated disaccharides
Carolyn G Chen et al.
Matrix biology : journal of the International Society for Matrix Biology, 90, 1-19 (2020-02-23)
Hyaluronan plays a key role in regulating inflammation and tumor angiogenesis. Of the three transmembrane hyaluronan synthases, HAS2 is the main pro-angiogenic enzyme responsible for excessive hyaluronan production. We discovered that HAS2 was degraded in vascular endothelial cells via autophagy
Fabio Galeotti et al.
Analytical chemistry, 83(17), 6770-6777 (2011-07-26)
A high-resolution online reverse-phase-high-performance liquid chromatography (RP-HPLC)-fluorescence detector (Fd)-electrospray ionization-mass spectrometry (ESI-MS) separation and structural characterization of disaccharides prepared from heparin (Hep), heparan sulfate (HS), and various low-molecular-weight (LMW)-Hep using heparin lyases and derivatization with 2-aminoacridone (AMAC) are described. A
Wing Lee Chan et al.
PLoS genetics, 14(3), e1007242-e1007242 (2018-03-22)
Gerodermia osteodysplastica (GO) is characterized by skin laxity and early-onset osteoporosis. GORAB, the responsible disease gene, encodes a small Golgi protein of poorly characterized function. To circumvent neonatal lethality of the GorabNull full knockout, Gorab was conditionally inactivated in mesenchymal
Eiki Maeda et al.
Electrophoresis, 28(16), 2927-2933 (2007-07-21)
A high-performance monitoring system for human blood glucose levels was developed using microchip electrophoresis with a plastic chip. The combination of reductive amination as glucose labeling with fluorescent 2-aminoacridone (AMAC) and glucose-borate complex formation realized the highly selective detection of
Produkty
Glycans play a key role in protein structure and disease; representation on cell surfaces is the glycome.
Numer pozycji handlu globalnego
| SKU | NUMER GTIN |
|---|---|
| 06627-25MG | 04061838646415 |
| 06627-100MG | 04061833276679 |
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