02070
Adenosine 5′-triphosphate P3-[1-(2-nitrophenyl)ethyl ester] disodium salt
≥95% (HPLC)
Synonim(y):
NPE caged ATP, Caged ATP
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Informacje o tej pozycji
Wzór empiryczny (zapis Hilla):
C18H21N6Na2O15P3
Numer CAS:
Masa cząsteczkowa:
700.29
UNSPSC Code:
41106305
PubChem Substance ID:
MDL number:
Pomoc techniczna
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Pozwól nam pomócassay
≥95% (HPLC)
storage temp.
−20°C
SMILES string
[Na+].[Na+].CC(OP([O-])(=O)OP([O-])(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n2cnc3c(N)ncnc23)c4ccccc4[N+]([O-])=O
InChI
1S/C18H23N6O15P3.2Na/c1-9(10-4-2-3-5-11(10)24(27)28)37-41(31,32)39-42(33,34)38-40(29,30)35-6-12-14(25)15(26)18(36-12)23-8-22-13-16(19)20-7-21-17(13)23;;/h2-5,7-9,12,14-15,18,25-26H,6H2,1H3,(H,29,30)(H,31,32)(H,33,34)(H2,19,20,21);;/q;2*+1/p-2/t9?,12-,14-,15-,18-;;/m1../s1
InChI key
DWGOHIKVVKFGGU-DZHDPEGHSA-L
Application
Adenosine 5′-triphosphate γ-(1-[2-nitrophenyl]ethyl) ester (“Caged” ATP) is used as a photolyzing substrate of luciferase-mediated firefly bioluminescence and other ATP-dependent photolytic processes. Caged ATP has also been used to study the dynamics of ATP-driven linear molecular motors such as myosin Va. Caged ATP is used to study intracellular mechanisms; Irradiation with a short light pulse of 360 nm wavelength releases the parent compound from its cage resulting in a time- and quantity-specific concentration increase of ATP within the cell; Relaxation of muscle fibres by photolysis of caged ATP.
Other Notes
Used to study intracellular mechanisms.; Irradiation with a short light pulse of 360 nm wavelength releases the parent compound from its cage, resulting in a time- and quantity-specific concentration increase of ATP within the cell.; Relaxation of muscle fibres by photolysis of caged ATP; Caged ATP as a tool in active transport research
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signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2
Klasa składowania
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_c
Not applicable
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Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.
Caged ATP as a tool in active transport research.
J H Kaplan
Society of General Physiologists series, 40, 385-396 (1986-01-01)
Direct observation of the myosin Va recovery stroke that contributes to unidirectional stepping along actin.
Shiroguchi K, Chin HF, et al.
PLoS Biology, e1001031-e1001031 (2011)
Y E Goldman et al.
Nature, 300(5894), 701-705 (1982-12-23)
A novel method has been developed for studying the reaction kinetics of the force-generating mechanism in muscle. Inert photolabile precursors of ATP or ADP are incorporated into muscle fibres having their surface membrane barrier removed. The nucleotide is then rapidly
Numer pozycji handlu globalnego
| SKU | NUMER GTIN |
|---|---|
| 8182480100 | 04022536431352 |
| 389560-500ML | 04061838127082 |
| 389560-100ML | 04061831971002 |